A binding site model and structure-activity relationships for the rat A3 adenosine receptor (Q28369257)

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C Gallo-Rodriguez

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N Melman

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M E Olah

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A P IJzerman

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G L Stiles

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K A Jacobson

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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language of work or name

English

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publication date

June 1994

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published in

Molecular Pharmacology

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volume

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issue

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page(s)

1101-11

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cites work

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This is not a G protein-coupled receptor.

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Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis

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The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells

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Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists

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Chemical modification of A1 adenosine receptors in rat brain membranes. Evidence for histidine in different domains of the ligand binding site

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Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors

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Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins

2 June 2018

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Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase

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Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.

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Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor

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12 December 2020

Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors

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12 December 2020

A steric and electrostatic comparison of three models for the agonist/antagonist binding site on the adenosine A1 receptor

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12 December 2020

Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines

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12 December 2020

Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists

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12 December 2020

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

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12 December 2020