Selective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cells (Q28368229)

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English	Selective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cells	scientific article

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title

Selective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cells (English)

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main subject

Pneumocystis carinii

object named as

Pneumocystis carinii

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based on heuristic

inferred from title

author name string

C C Dykstra

series ordinal

1

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D R McClernon

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2

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L P Elwell

series ordinal

3

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R R Tidwell

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4

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language of work or name

English

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publication date

September 1994

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published in

Antimicrobial Agents and Chemotherapy

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volume

38

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issue

9

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page(s)

1890-8

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cites work

Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia

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Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia

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Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis

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Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines

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20 March 2017

Inhibition of topoisomerases from Pneumocystis carinii by aromatic dicationic molecules

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20 March 2017

Structure-activity studies of dicationically substituted bis-benzimidazoles against Giardia lamblia: correlation of antigiardial activity with DNA binding affinity and giardial topoisomerase II inhibition

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DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting.

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29 September 2017

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide

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Sequence specificity of actinomycin D and Netropsin binding to pBR322 DNA analyzed by protection from DNase I

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DNA bending at adenine . thymine tracts

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PubMed Central

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29 September 2017

Sequence-directed bent DNA helix is the specific binding site for Crithidia fasciculata nicking enzyme

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DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells

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29 September 2017

Effect of minor groove binding drugs on mammalian topoisomerase I activity

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Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

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Molecular recognition of B-DNA by Hoechst 33258.

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Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures

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Structure-activity relationships of pentamidine analogs against Giardia lamblia and correlation of antigiardial activity with DNA-binding affinity

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Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature

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29 September 2017

Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide.

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29 September 2017

Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities

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29 September 2017

Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events

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29 September 2017

In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics

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29 September 2017

Aromatic amidines. Comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin

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Effect of drug-DNA interactions upon transcription initiation at the lac promoter

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Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavage

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ATP-independent DNA topoisomerase II as potential drug target in trypanosomes

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2 June 2018

Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4'-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage.

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2 June 2018

Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes

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Specific activation of transcription initiation by the sequence-specific DNA-binding agents distamycin A and netropsin.

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Cleavage of DNA by mammalian DNA topoisomerase II

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Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives

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The conformation of constitutive DNA interaction sites for eukaryotic DNA topoisomerase I on intrinsically curved DNAs

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Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles)

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12 December 2020

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Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study

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12 December 2020

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Amiloride intercalates into DNA and inhibits DNA topoisomerase II

1 reference

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PubMed

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12 December 2020

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Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage

1 reference

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PubMed

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12 December 2020

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Decatenation of kinetoplast DNA by topoisomerases

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/7810995

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12 December 2020

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Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7810995

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12 December 2020

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Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/7810995

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12 December 2020

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On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7810995

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.38.9.1890

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2221654

Fatcat ID

release_3ucmvspvrnctnh2uz6qtofpm54

0 references

OpenCitations bibliographic resource ID

2221654

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2221654

PMC publication ID

284658

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2221654

PubMed publication ID

7810995

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2221654

 

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