Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides (Q28368026)

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16 August 2024

R. M. Lloyd

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16 August 2024

M. H. Nguyen

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16 August 2024

D. L. Cannon

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16 August 2024

A. McMillan

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16 August 2024

N. Ilksoy

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16 August 2024

C. K. Chu

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16 August 2024

D. C. Liotta

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H. Z. Bazmi

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16 August 2024

J. W. Mellors

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full work available at URL

16 August 2024

language of work or name

English

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publication date

April 1993

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https://europepmc.org/articles/pmc187791?pdf=render

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Portable Document Format

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open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7684216

https://europepmc.org/articles/PMC187791

16 August 2024

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16 August 2024

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Portable Document Format

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open access

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https://journals.asm.org/doi/pdf/10.1128/AAC.37.4.875

16 August 2024

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Antimicrobial Agents and Chemotherapy

16 August 2024

published in

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volume

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issue

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page(s)

875-81

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cites work

Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

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Delayed treatment with combinations of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis

20 March 2017

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

20 March 2017

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Comparison of inhibitory activities of various antiretroviral agents against particle-derived and recombinant human immunodeficiency virus type 1 reverse transcriptases

20 March 2017

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Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

20 March 2017

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Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture

20 March 2017

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Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication

20 March 2017

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Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

20 March 2017

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Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture

20 March 2017

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Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

20 March 2017

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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

20 March 2017

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Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues

20 March 2017

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The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro

20 March 2017

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Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma

20 March 2017

1 reference

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In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase

20 March 2017

1 reference

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The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187791

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187791

The safety and pharmacokinetics of a reverse transcriptase inhibitor, 3TC, in patients with HIV infection

20 March 2017

1 reference

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Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

20 March 2017

1 reference

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Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine

20 March 2017

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

20 March 2017

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

7 April 2017

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Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity

7 April 2017

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Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay

29 September 2017

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Use of recombinant retroviruses to characterize the activity of antiretroviral compounds

29 September 2017

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HIV-1 Reverse Transcriptase: Structure Predictions for the Polymerase Domain

29 September 2017

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Insights into HIV chemotherapy

29 September 2017

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29 September 2017

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Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys

29 September 2017

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Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication

29 September 2017

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2 June 2018

Identifiers

DOI

10.1128/AAC.37.4.875

1 reference

1 reference

1 reference

1 reference