The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia (Q28354267)

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G Del Giudice

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R Rappuoli

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M Zoratti

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E Papini

Journal of Clinical Investigation

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language of work or name

English

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publication date

September 2001

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published in

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volume

108

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issue

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page(s)

929-37

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Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity

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A pH-sensitive channel regulates urea access to Helicobacter pylori urease

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Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant

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12 December 2020

Acetyl-CoA carboxylase activity in Helicobacter pylori and the requirement of increased CO2 for growth

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12 December 2020

Inhibition of the vacuolating and anion channel activities of the VacA toxin of Helicobacter pylori

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12 December 2020

Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells

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12 December 2020

Identifiers

DOI

10.1172/JCI13045

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1 reference

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PubMed publication ID

11560962

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