Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery (Q28327002)

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scientific article published on October 1, 1992

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English	Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery	scientific article published on October 1, 1992

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instance of

scholarly article

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title

Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery (English)

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main subject

drug discovery

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Candida albicans

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based on heuristic

inferred from title

fluorenes

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stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

author name string

J. M. Fostel

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

D. A. Montgomery

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

L. L. Shen

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

language of work or name

English

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publication date

October 1992

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full work available at URL

https://europepmc.org/articles/PMC245467

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HTML

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

https://europepmc.org/articles/PMC245467?pdf=render

file format

PDF

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1332588

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332588

retrieved

14 September 2022

published in

Antimicrobial Agents and Chemotherapy

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volume

36

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issue

10

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page(s)

2131-8

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cites work

The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication

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29 September 2017

Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

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29 September 2017

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

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Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome

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An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

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29 September 2017

DNA topoisomerase II is required at the time of mitosis in yeast

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PubMed Central

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29 September 2017

Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

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PubMed Central

reference URL

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29 September 2017

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

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PubMed Central

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29 September 2017

DNA topoisomerase poisons as antitumor drugs

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PubMed Central

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29 September 2017

Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

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29 September 2017

Catalytic function of DNA topoisomerase II.

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29 September 2017

Interaction between DNA and Escherichia coli protein omega. Formation of a complex between single-stranded DNA and omega protein

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29 September 2017

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

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29 September 2017

Mechanism of the reaction catalyzed by the DNA untwisting enzyme: Attachment of the enzyme to 3′-terminus of the nicked DNA

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Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

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Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA

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Double strand DNA cleavage by type II DNA topoisomerase from Drosophila melanogaster

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Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization

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Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity.

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2 June 2018

Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities

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Cleavage of DNA by mammalian DNA topoisomerase II

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Anticandidal activity of eupolauridine and onychine, alkaloids from Cleistopholis patens

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Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

based on heuristic

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Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA topoisomerases as targets for cancer therapy

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

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8 Multiple forms of rat liver type I topoisomerase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1332588

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.36.10.2131

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Fatcat ID

release_i75tlfbe5fb4tdllaheq4fjfpa

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PMC publication ID

245467

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PubMed publication ID

1332588

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ResearchGate publication ID

21822298

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