Roles of cyclophilins in cancers and other organ systems (Q28307050)

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Min Li

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Hui Yang

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Hong Chai

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William Fisher

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Changyi Chen

Cyclophilin-40: evidence for a dimeric complex with hsp90.

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language of work or name

English

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publication date

March 2005

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published in

World Journal of Surgery

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volume

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issue

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page(s)

276-80

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cites work

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Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae

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Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting

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Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60

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Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

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Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria.

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The biochemistry of programmed cell death

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12 December 2020

Rapamycin: a novel immunosuppressive macrolide

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12 December 2020

Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23

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12 December 2020

Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans-isomerase

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Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides

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The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

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Quantitative comparison of rapamycin and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction

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Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6

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Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer

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12 December 2020

Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells.

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12 December 2020

Isolation and characterization of a 40-kDa cyclophilin-related protein

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12 December 2020

Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization

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12 December 2020

Peptidylproline cis/trans isomerases

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12 December 2020

Structural insights into the catalytic mechanism of cyclophilin A

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12 December 2020

Host cyclophilin A mediates HIV-1 attachment to target cells via heparans

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12 December 2020

Heat shock proteins: molecular chaperones of protein biogenesis.

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12 December 2020

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

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12 December 2020

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

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12 December 2020

Protein Folding In Vivo: Unraveling Complex Pathways

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12 December 2020

Active site residues of cyclophilin A are crucial for its signaling activity via CD147

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12 December 2020

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

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12 December 2020

CD147 is a signaling receptor for cyclophilin B

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12 December 2020

Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2+ and Oxidant Stress

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12 December 2020

Cyclophilins and their possible role in the stress response

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12 December 2020

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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12 December 2020

Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors

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12 December 2020

Calcium signalling in T cells stimulated by a cyclophilin B-binding protein

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12 December 2020

Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer.

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12 December 2020

Cloning and subcellular localization of human mitochondrial hsp70

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12 December 2020

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

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12 December 2020

Cyclophilin A is a secreted growth factor induced by oxidative stress

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12 December 2020

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

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12 December 2020

Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies

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12 December 2020

Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages

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12 December 2020

Enzyme assembly after de novo synthesis in rabbit reticulocyte lysate involves molecular chaperones and immunophilins

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12 December 2020

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition

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12 December 2020

The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms

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12 December 2020

Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas

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12 December 2020

Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands

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12 December 2020

Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock

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12 December 2020

Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix

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12 December 2020

Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes

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12 December 2020

Allosteric inhibition of the Ca2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides

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12 December 2020

A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24-restricted and tumor-specific CTLs

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12 December 2020

Increased expression of extracellular matrix metalloproteinase inducer in rheumatoid synovium

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12 December 2020

The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins

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12 December 2020

Modulation of cyclophilin gene expression by N-4-(hydroxyphenyl)retinamide: association with reactive oxygen species generation and apoptosis

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12 December 2020

Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells

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12 December 2020

Phase 1 clinical study of cyclophilin B peptide vaccine for patients with lung cancer

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12 December 2020

The mechanism of action of FK-506 and cyclosporin A.

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12 December 2020

A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, and C have nuclease activity

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12 December 2020

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

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12 December 2020

Kinetic evidence for a heart mitochondrial pore activated by Ca2+, inorganic phosphate and oxidative stress. A potential mechanism for mitochondrial dysfunction during cellular Ca2+ overload

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12 December 2020

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

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12 December 2020