Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging (Q28305337)

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scientific article published on February 11, 2011

Language	Label	Description	Also known as
English	Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging	scientific article published on February 11, 2011

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scholarly article

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Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging (English)

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Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging (English)

1 reference

10.1002/PBC.23015

https://api.crossref.org/works/10.1002/PBC.23015

24 November 2024

plexiform neurofibroma

1 reference

based on heuristic

inferred from title

animal disease model

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

Timothy P Cripe

10

object named as

Timothy P Cripe

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author name string

Jianqiang Wu

1

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Eva Dombi

2

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Edwin Jousma

3

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Diana Lindquist

5

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Mi-Ok Kim

7

0 references

Aerang Kim

8

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Nancy Ratner

11

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R. Scott Dunn

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

Beverly M. Schnell

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

Brigitte C. Widemann

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

language of work or name

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publication date

February 2012

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11 February 2011

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

full work available at URL

https://europepmc.org/articles/pmc3128176?pdf=render

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

https://europepmc.org/articles/PMC3128176

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

https://europepmc.org/articles/PMC3128176?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

https://doi.org/10.1002/pbc.23015

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21319287

24 November 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fpbc.23015

1 reference

10.1002/PBC.23015

https://api.crossref.org/works/10.1002/PBC.23015

24 November 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pbc.23015

1 reference

10.1002/PBC.23015

https://api.crossref.org/works/10.1002/PBC.23015

24 November 2024

Pediatric Blood & Cancer

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58

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2

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173-80

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describes a project that uses

magnetic resonance imaging

1 reference

based on heuristic

inferred from title

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

20 March 2017

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

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20 March 2017

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

20 March 2017

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

7 April 2017

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

7 April 2017

Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

How does the Schwann cell lineage form tumors in NF1?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

The NF1 tumor suppressor critically regulates TSC2 and mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

BAY 43-9006: preclinical data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

GTPase activating proteins: critical regulators of intracellular signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Hyperactive Ras as a therapeutic target in neurofibromatosis type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Statistical analysis of in vivo tumor growth experiments

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128176

29 September 2017

Neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Automated detection and volume measurement of plexiform neurofibromas in neurofibromatosis 1 using magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Liquid chromatography-tandem mass spectrometric assay for sorafenib and sorafenib-glucuronide in mouse plasma and liver homogenate and identification of the glucuronide metabolite

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Drug discovery: inhibitors that activate

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

An extensive study on isosorbide-5-mononitrate acid adducts for quantification in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry and its application to bioequivalence sample analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21319287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromatosis 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21319287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1002/PBC.23015

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