Examination of 209 drugs for inhibition of cytochrome P450 2C8 (Q28298519)

https://api.crossref.org/works/10.1177%2F0091270004270642

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Gemfibrozil greatly increases plasma concentrations of cerivastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Learning from the cerivastatin experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

The xenobiotic inhibitor profile of cytochrome P4502C8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Drug interactions of paclitaxel metabolism in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Validated assays for human cytochrome P450 activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Bioavailability and metabolism of mometasone furoate: pharmacology versus methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Topical pharmacology of imidazole antifungals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Current progress on esterases: from molecular structure to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004270642