Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells (Q28297767)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells (English)

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24 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Erina Fukunaga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Yasumichi Inoue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Setsuro Komiya

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24 December 2019

Kana Horiguchi

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Kouichiro Goto

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24 December 2019

Masao Saitoh

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24 December 2019

Daizo Koinuma

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Aki Hanyu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Takeshi Imamura

1 reference

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24 December 2019

language of work or name

English

0 references

publication date

16 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

24 December 2019

published in

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24 December 2019

volume

283

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24 December 2019

issue

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24 December 2019

page(s)

35660-35667

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24 December 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Substrate targeting in the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Smurf2 up-regulation activates telomere-dependent senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

The Nedd4-like family of E3 ubiquitin ligases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

mGrb10 interacts with Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M710496200

21 January 2018

Identifiers

DOI

10.1074/JBC.M710496200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18927080%20AND%20SRC:MED&resulttype=core&format=json