Opposing LSD1 complexes function in developmental gene activation and repression programmes (Q28295495)

Euchromatic histone lysine N-methyltransferase 2

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Euchromatic histone methyltransferase 1

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REST corepressor 1

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Zinc finger E-box binding homeobox 1

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Histone deacetylase 2

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Chromobox 4

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Nuclear receptor corepressor 1

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Ligand dependent nuclear receptor corepressor

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Lysine (K)-specific demethylase 1A

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C-terminal binding protein 1

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Histone deacetylase 1

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Recombination signal binding protein for immunoglobulin kappa J region

1 reference

Ivan Garcia-Bassets

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Friederike L Jayes

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Kenneth S Korach

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Christopher K Glass

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Kenneth A Ohgi

object named as

Kenneth A Ohgi

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author name string

Jianxun Wang

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Kathleen Scully

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Xiaoyan Zhu

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Ling Cai

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Jie Zhang

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Gratien G Prefontaine

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Anna Krones

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Ping Zhu

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Forrest Liu

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Havilah Taylor

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Jean Lozach

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Xiang-Dong Fu

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Michael G Rosenfeld

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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language of work or name

English

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publication date

19 April 2007

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published in

Nature

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volume

446

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issue

7138

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page(s)

882-7

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cites work

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The diverse functions of histone lysine methylation

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REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

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The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

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CoREST: a functional corepressor required for regulation of neural-specific gene expression

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Regulation of neuronal traits by a novel transcriptional complex

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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

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Coordinated histone modifications mediated by a CtBP co-repressor complex

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CoREST is an integral component of the CoREST- human histone deacetylase complex

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Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1

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ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

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A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

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A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes

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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

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LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

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Histone demethylation by a family of JmjC domain-containing proteins

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JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

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Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

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Mouse knockout solves endocrine puzzle and promotes new pituitary lineage model

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Pituitary development: regulatory codes in mammalian organogenesis

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Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

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Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth

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GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

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Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

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RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes

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Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis

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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

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Role of PROP1 in Pituitary Gland Growth

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Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter.

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Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice.

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Dwarf mice produced by genetic ablation of growth hormone-expressing cells

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Transgenic mice with inducible dwarfism.

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Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification

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Identification of a Zinc Finger Protein that Inhibits IL-2 Gene Expression

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ZEB represses transcription through interaction with the corepressor CtBP

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Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

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Interference with the Expression of a Novel Human Polycomb Protein, hPc2, Results in Cellular Transformation and Apoptosis

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The polycomb protein Pc2 is a SUMO E3

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WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development

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Pituitary cell lines and their endocrine applications.

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Insights from the study of animals lacking functional estrogen receptor

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Identification of the novel player deltaEF1 in estrogen transcriptional cascades

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Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene

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Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin

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