Glycan array screening reveals a candidate ligand for Siglec-8 (Q28295084)

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5 January 2020

title

Glycan array screening reveals a candidate ligand for Siglec-8 (English)

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5 January 2020

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5 January 2020

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5 January 2020

Bruce S Bochner

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5 January 2020

Richard A Alvarez

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5 January 2020

Padmaja Mehta

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5 January 2020

Nicolai V Bovin

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5 January 2020

John R White

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5 January 2020

language of work or name

English

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publication date

24 November 2004

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Journal of Biological Chemistry

5 January 2020

published in

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5 January 2020

volume

280

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issue

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5 January 2020

page(s)

4307-4312

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Siglecs in the immune system

5 January 2020

cites work

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Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution

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A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9.

21 January 2018

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Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin

21 January 2018

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High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family

21 January 2018

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Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1

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Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells

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A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33.

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Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms

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Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily

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Molecular characterization of a Siglec8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the Siglec8 gene

21 January 2018

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Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes

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Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis

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New aspects of siglec binding specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins

21 January 2018

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Cutting edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1)

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Fluorescent carbohydrate probes for cell lectins.

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Monosaccharides attached to agarose.

21 January 2018

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The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils

21 January 2018

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