Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1 (Q28283017)

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M Rizzi

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T J Grob

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B Hügli

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V A Reddy

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A-C Andres

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B E Torbett

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A Tobler

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M F Fey

Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.

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language of work or name

English

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publication date

30 March 2006

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2030-9

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cites work

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Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.

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TP53 family members and human cancers

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

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Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors

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Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B

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Definition of a consensus binding site for p53

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Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses.

21 January 2018

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Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer

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Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors.

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Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

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Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53

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Worms gang up on bacteria

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DeltaNp73beta is active in transactivation and growth suppression.

21 January 2018

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p53 upregulates death receptor 4 expression through an intronic p53 binding site

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products

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Viral oncoproteins discriminate between p53 and the p53 homolog p73.

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p73: Friend or foe in tumorigenesis

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PUMA, a novel proapoptotic gene, is induced by p53

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Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

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Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer

21 January 2018

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Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells.

21 January 2018

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Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1

21 January 2018

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The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic p53-binding site.

21 January 2018

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p53-independent role of MDM2 in TGF-beta1 resistance

21 January 2018

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Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns

21 January 2018

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

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p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

21 January 2018

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Analysis of p53 "latency" and "activation" by fluorescence correlation spectroscopy. Evidence for different modes of high affinity DNA binding.

21 January 2018

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The tumor-suppressive functions of the human INK4A locus

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p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

The fundamental role of epigenetic events in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209240

inferred from DOI database lookup

7 January 2021

based on heuristic

Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites

1 reference

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