Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling (Q28289659)

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English	Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling	scientific article

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4 January 2020

Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling (English)

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4 January 2020

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Xiao-Feng Le

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Amy Lammayot

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David Gold

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Yiling Lu

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Weiqun Mao

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Teresa Chang

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Adarsh Patel

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25 October 2004

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Journal of Biological Chemistry

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3

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2092-2104

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4 January 2020

The deaf and the dumb: the biology of ErbB-2 and ErbB-3

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Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer

1 reference

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Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells

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ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth

1 reference

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Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs

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A model of molecular interactions on short oligonucleotide microarrays

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Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

1 reference

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The PI3K-PDK1 connection: more than just a road to PKB

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The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells

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Mechanisms of Taxol resistance related to microtubules.

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The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis

1 reference

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

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21 January 2018

Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer

1 reference

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The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures

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The human and mouse replication-dependent histone genes

1 reference

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21 January 2018

Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells.

1 reference

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A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions

1 reference

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Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

1 reference

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21 January 2018

A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle

1 reference

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DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

1 reference

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21 January 2018

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10.1074/JBC.M403080200

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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4 January 2020

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15504738%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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