A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction (Q28288539)

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English	A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

title

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction (English)

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

main subject

structural biology

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author

Chieri Tomomori-Sato

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Chieri Tomomori-Sato

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3

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Joan W. Conaway

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Joan W Conaway

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5

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author name string

Kuang-Lei Tsai

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1

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

Shigeo Sato

series ordinal

2

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

Ronald C Conaway

series ordinal

4

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stated in

Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

Francisco J Asturias

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6

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

language of work or name

English

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publication date

7 April 2013

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

published in

Nature Structural & Molecular Biology

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

volume

20

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

issue

5

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

page(s)

611-619

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Europe PubMed Central

PubMed publication ID

23563140

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24 June 2017

cites work

Structure of the Mediator head module

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PubMed Central

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Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II

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20 March 2017

Interaction of the Mediator Head Module with RNA Polymerase II

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PubMed Central

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The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder

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20 March 2017

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Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

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Mediator head module structure and functional interactions

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20 March 2017

Mediator structural conservation and implications for the regulation mechanism

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20 March 2017

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

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CDK8 is a stimulus-specific positive coregulator of p53 target genes

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Mediator as a general transcription factor

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Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3

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20 March 2017

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Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

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Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s

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The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

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A kinase-cyclin pair in the RNA polymerase II holoenzyme.

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Conserved structures of mediator and RNA polymerase II holoenzyme

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Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

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Identifiers

DOI

10.1038/NSMB.2549

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Europe PubMed Central

PubMed publication ID

23563140

retrieved

24 June 2017

Dimensions Publication ID

1025524527

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PMC publication ID

3648612

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PubMed publication ID

23563140

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23563140

retrieved

24 June 2017

ResearchGate publication ID

236127868

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