Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma (Q28287898)

object named as

Robert M Bachoo

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author name string

Keith L Ligon

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Emmanuelle Huillard

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Shwetal Mehta

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Santosh Kesari

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Hongye Liu

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John A Alberta

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Michael Kane

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David N Louis

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David J Anderson

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Charles D Stiles

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David H Rowitch

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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language of work or name

English

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publication date

15 February 2007

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503-17

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cites work

1 reference

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Lineage dependency and lineage-survival oncogenes in human cancer

20 March 2017

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Development of NG2 neural progenitor cells requires Olig gene function

20 March 2017

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A novel function of OLIG2 to suppress human glial tumor cell growth via p27Kip1 transactivation

20 March 2017

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Neural stem cells and the origin of gliomas

20 March 2017

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Lost in transcription: p21 repression, mechanisms, and consequences

20 March 2017

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Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

20 March 2017

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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

20 March 2017

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Identification of human brain tumour initiating cells

20 March 2017

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

20 March 2017

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Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation

20 March 2017

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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

20 March 2017

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The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

20 March 2017

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High frequency of mutations of the PIK3CA gene in human cancers

20 March 2017

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Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex

20 March 2017

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Identification of a cancer stem cell in human brain tumors

20 March 2017

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Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors

20 March 2017

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Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

20 March 2017

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Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

20 March 2017

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Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells

20 March 2017

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Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells

20 March 2017

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Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection

20 March 2017

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

20 March 2017

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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

7 April 2017

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

7 April 2017

1 reference

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"Stemness": transcriptional profiling of embryonic and adult stem cells

7 April 2017

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

7 April 2017

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Origin of oligodendrocytes in the subventricular zone of the adult brain.

7 April 2017

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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

29 September 2017

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The bad seed: PDGF receptors link adult neural progenitors to glioma stem cells

29 September 2017

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29 September 2017

Brain tumour stem cells

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Expression profile of an operationally-defined neural stem cell clone.

29 September 2017

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Neuronal fate determinants of adult olfactory bulb neurogenesis

29 September 2017

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bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

29 September 2017

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Development of novel targeted therapies in the treatment of malignant glioma

29 September 2017

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Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers

29 September 2017

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An analysis of the gene expression program of mammalian neural progenitor cells

29 September 2017

1 reference

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Shared oligodendrocyte lineage gene expression in gliomas and oligodendrocyte progenitor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810344

Disruption of differentiation in human cancer: AML shows the way.

29 September 2017

1 reference

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A stem cell molecular signature

29 September 2017

1 reference

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Focus on central nervous system neoplasia

29 September 2017

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Formation of the androgen receptor transcription complex

29 September 2017

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Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas.

29 September 2017

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Malignant glioma: genetics and biology of a grave matter.

29 September 2017

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Stem cells and pattern formation in the nervous system: the possible versus the actual

29 September 2017

1 reference

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The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

29 September 2017

1 reference

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Molecular pathogenesis of malignant gliomas

29 September 2017

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P16 deletion and mutation analysis in human brain tumors

29 September 2017

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Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

29 September 2017

1 reference

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Translational control of p27Kip1 accumulation during the cell cycle

29 September 2017

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Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors

29 September 2017

1 reference

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A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells

2 June 2018

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Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

2 June 2018

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PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

2 June 2018

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Involvement of the Olig2 transcription factor in cholinergic neuron development of the basal forebrain

27 November 2018

1 reference

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p53 suppresses the self-renewal of adult neural stem cells.

27 November 2018

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p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity

27 November 2018

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Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice.

27 November 2018

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Somatic mutations of EGFR in colorectal cancers and glioblastomas

27 November 2018

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Immunolocalization of the oligodendrocyte transcription factor 1 (Olig1) in brain tumors

27 November 2018

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Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia

27 November 2018

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Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro

27 November 2018

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Expression of the Oligodendroglial Lineage-Associated Markers Olig1 and Olig2 in Different Types of Human Gliomas

27 November 2018

1 reference

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The expression of p73, p21 and MDM2 proteins in gliomas

27 November 2018

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Immunohistochemical markers for prognosis of oligodendroglial neoplasms

27 November 2018

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The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.

27 November 2018

1 reference

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The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.

27 November 2018

1 reference

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Production and analysis of neurospheres from acutely dissociated and postmortem CNS specimens

27 November 2018

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Cell cycle regulators (p21, p53, pRb) in oligodendrocytic tumors: a study by novel tumor microarray technique.

27 November 2018

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Changes in the immunologic phenotype of human malignant glioma cells after passaging in vitro.

27 November 2018

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Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex

27 November 2018

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Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2.

27 November 2018

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Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons

27 November 2018

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OLIG2 as a specific marker of oligodendroglial tumour cells.

27 November 2018

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PTEN mutations in gliomas and glioneuronal tumors.

27 November 2018

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PTEN gene mutations are seen in high-grade but not in low-grade gliomas

27 November 2018

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Hematopoietic stem cell quiescence maintained by p21cip1/waf1

27 November 2018

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12 December 2020

Expression of an altered epidermal growth factor receptor by human glioblastoma cells

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12 December 2020

Epidermal growth factor receptor and Ink4a/Arf

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12 December 2020

Negative control elements of the cell cycle in human tumors

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12 December 2020

Isolation of cancer stem cells from adult glioblastoma multiforme

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12 December 2020

TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme

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12 December 2020

10.1016/J.NEURON.2007.01.009

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

17296553

1 reference