Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit (Q28286541)

24 June 2017

title

Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit (English)

1 reference

24 June 2017

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1 reference

GOA release 2020-03-11

author name string

Ting-Yu Yeh

1 reference

24 June 2017

Anna K Kowalska

1 reference

24 June 2017

Brett R Scipioni

1 reference

24 June 2017

Frances Ka Yan Cheong

1 reference

24 June 2017

Meiying Zheng

1 reference

24 June 2017

Urszula Derewenda

1 reference

24 June 2017

Zygmunt S Derewenda

1 reference

24 June 2017

Trina A Schroer

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24 June 2017

language of work or name

English

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publication date

1 March 2013

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24 June 2017

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24 June 2017

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24 June 2017

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24 June 2017

page(s)

1023-1035

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Dynactin's pointed-end complex is a cargo-targeting module

24 June 2017

cites work

1 reference

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20 March 2017

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The p25 subunit of the dynactin complex is required for dynein-early endosome interaction

20 March 2017

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Polo-like kinase 1 phosphorylation of p150 Glued facilitates nuclear envelope breakdown during prophase

20 March 2017

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Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

20 March 2017

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Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint

20 March 2017

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Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

20 March 2017

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Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint

20 March 2017

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ZW10 links mitotic checkpoint signaling to the structural kinetochore.

20 March 2017

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The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint

20 March 2017

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Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores

20 March 2017

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Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

20 March 2017

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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

20 March 2017

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Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end

20 March 2017

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ZW10 helps recruit dynactin and dynein to the kinetochore

20 March 2017

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Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

20 March 2017

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Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin

20 March 2017

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Two activators of microtubule-based vesicle transport

20 March 2017

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3D-Jury: a simple approach to improve protein structure predictions

20 March 2017

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Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates

7 April 2017

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High mitotic activity of Polo-like kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells

7 April 2017

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Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments

29 September 2017

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Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Polo-like kinase1 is required for recruitment of dynein to kinetochores during mitosis

29 September 2017

1 reference

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The Plk1-dependent phosphoproteome of the early mitotic spindle

29 September 2017

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Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation

29 September 2017

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Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F.

29 September 2017

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Dynein at the kinetochore: Timing, Interactions and Functions

29 September 2017

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Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity

29 September 2017

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Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis.

29 September 2017

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Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment

29 September 2017

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A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Evaluation of 3D-Jury on CASP7 models.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Dynactins p25 and p27 are predicted to adopt the LbetaH fold.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616283

Purification of dynactin and dynein from brain tissue.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.30

Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.30

Analysis of the sequence and structural features of the left-handed beta-helical fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.30

Mechanism of dynamitin-mediated disruption of dynactin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.30

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.30

Autoantibodies to chromosomal domains in rheumatic diseases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23455152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23455152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2013.30

1 reference

release_7gwwfscsa5ac7fm35e5c76lbz4

24 June 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7gwwfscsa5ac7fm35e5c76lbz4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3616283

0 references

1 reference