Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy (Q28269627)

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English	Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy	scientific article

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title

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy (English)

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main subject

leukemia

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based on heuristic

inferred from title

author

Tony Kouzarides

series ordinal

34

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Panagis Filippakopoulos

object named as

Panagis Filippakopoulos

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12

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Andrew Bannister

object named as

Andrew Bannister

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16

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Susanne Müller

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Susanne Müller

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29

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Stefan Knapp

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Stefan Knapp

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37

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Heidi Olzscha

object named as

Heidi Olzscha

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7

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Paul E. Brennan

object named as

Paul E Brennan

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26

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Rab K Prinjha

series ordinal

35

object named as

Rab Prinjha

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Ka Hing Che

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15

object named as

Ka Hing Che

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Dave Lugo

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21

object named as

Dave Lugo

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Carl M. Philpott

series ordinal

10

object named as

Martin Philpott

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Sarah Picaud

series ordinal

1

object named as

Sarah Picaud

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Jürg Schwaller

series ordinal

36

object named as

Jürg Schwaller

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Anthony Tumber

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11

object named as

Anthony Tumber

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Chas Bountra

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25

object named as

Chas Bountra

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Alison O'Mahony

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27

object named as

Alison O'Mahony

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Octovia P Monteiro

series ordinal

8

object named as

Octovia Monteiro

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Clarence Yapp

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13

object named as

Clarence Yapp

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Angeliki Thanasopoulou

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3

object named as

Angeliki Thanasopoulou

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Katharina Leonards

series ordinal

4

object named as

Katharina Leonards

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Marjeta Urh

series ordinal

32

object named as

Marjeta Urh

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Danette Daniels

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31

object named as

Danette L Daniels

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author name string

Oleg Fedorov

series ordinal

2

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Katherine Jones

series ordinal

5

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Julia Meier

series ordinal

6

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Sarah Martin

series ordinal

9

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Christopher Wells

series ordinal

14

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Samuel Robson

series ordinal

17

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Umesh Kumar

series ordinal

18

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Nigel Parr

series ordinal

19

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Kevin Lee

series ordinal

20

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Philip Jeffrey

series ordinal

22

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Simon Taylor

series ordinal

23

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Matteo L Vecellio

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24

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Sharlene Velichko

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28

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Duncan Hay

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30

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Nicholas B La Thangue

series ordinal

33

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language of work or name

English

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publication date

1 December 2015

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published in

Cancer Research

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volume

75

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issue

23

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page(s)

5106-19

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cites work

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Selective inhibition of BET bromodomains

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CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

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Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

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29 September 2017

The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain.

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29 September 2017

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29 September 2017

Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia

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29 September 2017

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29 September 2017

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2 June 2018

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.

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Impairing MLL-fusion gene-mediated transformation by dissecting critical interactions with the lens epithelium-derived growth factor (LEDGF/p75).

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27 November 2018

Systematic in vivo structure-function analysis of p300 in hematopoiesis

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27 November 2018

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27 November 2018

Mechanism of p300 specific histone acetyltransferase inhibition by small molecules

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27 November 2018

Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.

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27 November 2018

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

1 reference

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PubMed

reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/0008-5472.CAN-15-0236

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3017894

OpenCitations bibliographic resource ID

3017894

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3017894

PMC publication ID

4948672

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3017894

PubMed publication ID

26552700

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3017894

 

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