Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling (Q28264548)

23 June 2017

title

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling (English)

1 reference

23 June 2017

Ruoyi Qiu

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23 June 2017

Vanessa C DeRocco

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23 June 2017

Credle Harris

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23 June 2017

Anushi Sharma

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23 June 2017

Manju M Hingorani

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23 June 2017

Dorothy A Erie

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23 June 2017

Keith R Weninger

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23 June 2017

language of work or name

English

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publication date

13 April 2012

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23 June 2017

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23 June 2017

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23 June 2017

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23 June 2017

page(s)

2528-2540

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Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS

23 June 2017

cites work

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Crystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair

20 March 2017

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The alternating ATPase domains of MutS control DNA mismatch repair

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Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair

20 March 2017

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The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

20 March 2017

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Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

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hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

20 March 2017

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Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair

20 March 2017

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The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch

20 March 2017

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Mechanism of MutS searching for DNA mismatches and signaling repair

20 March 2017

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Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6

20 March 2017

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Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS.

29 September 2017

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Atomic force microscopy captures MutS tetramers initiating DNA mismatch repair.

29 September 2017

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Beyond the random coil: stochastic conformational switching in intrinsically disordered proteins

29 September 2017

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Chemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli

29 September 2017

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MutS switches between two fundamentally distinct clamps during mismatch repair

29 September 2017

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Four-Color Single-Molecule Fluorescence with Noncovalent Dye Labeling to Monitor Dynamic Multimolecular Complexes

29 September 2017

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Three-dimensional molecular modeling with single molecule FRET.

29 September 2017

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Optimizing Methods to Recover Absolute FRET Efficiency from Immobilized Single Molecules

29 September 2017

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Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry

29 September 2017

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Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes

29 September 2017

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29 September 2017

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Conformational change in MSH2-MSH6 upon binding DNA coupled to ATPase activity

29 September 2017

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Dynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6.

29 September 2017

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29 September 2017

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29 September 2017

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Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.

29 September 2017

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Contribution of Msh2 and Msh6 subunits to the asymmetric ATPase and DNA mismatch binding activities of Saccharomyces cerevisiae Msh2-Msh6 mismatch repair protein

29 September 2017

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Theory of photon statistics in single-molecule Förster resonance energy transfer

29 September 2017

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Asymmetric ATP binding and hydrolysis activity of the Thermus aquaticus MutS dimer is key to modulation of its interactions with mismatched DNA.

29 September 2017

1 reference

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DNA bending and unbending by MutS govern mismatch recognition and specificity

29 September 2017

1 reference

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Mismatch recognition-coupled stabilization of Msh2-Msh6 in an ATP-bound state at the initiation of DNA repair

29 September 2017

1 reference

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ATP-hydrolysis-dependent conformational switch modulates the stability of MutS-mismatch complexes

29 September 2017

1 reference

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Oligomerization of a MutS mismatch repair protein from Thermus aquaticus

29 September 2017

1 reference

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hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

29 September 2017

1 reference

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The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair

29 September 2017

1 reference

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Heteroduplex DNA and ATP induced conformational changes of a MutS mismatch repair protein from Thermus aquaticus

2 June 2018

1 reference

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The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair

2 June 2018

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Differential and simultaneous adenosine di- and triphosphate binding by MutS.

21 January 2018

1 reference

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Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis

21 January 2018

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Mutations in the nucleotide-binding domain of MutS homologs uncouple cell death from cell survival.

21 January 2018

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Evidence for sequential action of two ATPase active sites in yeast Msh2-Msh6.

21 January 2018

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Direct observation of three conformations of MutS protein regulated by adenine nucleotides

21 January 2018

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ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

21 January 2018

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Inhibition of Msh6 ATPase activity by mispaired DNA induces a Msh2(ATP)-Msh6(ATP) state capable of hydrolysis-independent movement along DNA.

21 January 2018

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Effects of Cisplatin binding to DNA on the dynamics of the E. Coli MutS dimer.

21 January 2018

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Modulation of MutS ATP hydrolysis by DNA cofactors

21 January 2018

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12 December 2020

DNA mismatch repair and cancer

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12 December 2020

Assembly and molecular activities of the MutS tetramer

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12 December 2020

Organized arrays of individual DNA molecules tethered to supported lipid bilayers

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12 December 2020

A simple fluorescent method for detecting mismatched DNAs using a MutS-fluorophore conjugate

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12 December 2020

Signaling mismatch repair in cancer

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12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2012.95

1 reference

OpenCitations bibliographic resource ID

23 June 2017

4724971

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4724971

1 reference