Human antibody-Fc receptor interactions illuminated by crystal structures (Q28252414)

The crystal structure of IgE Fc reveals an asymmetrically bent conformation

20 April 2017

1 reference

Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc

20 April 2017

1 reference

Crystallographic structure of an intact IgG1 monoclonal antibody

20 April 2017

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

20 April 2017

1 reference

The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling

20 April 2017

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20 April 2017

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Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

20 April 2017

1 reference

Molecular basis for immune complex recognition: a comparison of Fc-receptor structures

20 April 2017

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Crystal structure of the soluble form of the human fcgamma-receptor IIb: a new member of the immunoglobulin superfamily at 1.7 A resolution

20 April 2017

1 reference

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

20 April 2017

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The structure of a human type III Fcgamma receptor in complex with Fc

20 April 2017

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The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms

20 April 2017

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Crystal structure of the ectodomain of human FcalphaRI

20 April 2017

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Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors

20 April 2017

1 reference

The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a

20 April 2017

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The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha

20 April 2017

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FcalphaRI-positive liver Kupffer cells: reappraisal of the function of immunoglobulin A in immunity

20 April 2017

1 reference

Convergent solutions to binding at a protein-protein interface

20 April 2017

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Recognition of immunoglobulins by Fcgamma receptors

20 April 2017

1 reference

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

20 April 2017

1 reference

Immunotherapy: past, present and future

20 April 2017

1 reference

The three-dimensional structure of an intact monoclonal antibody for canine lymphoma

20 April 2017

1 reference

Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility

21 January 2018

1 reference

Human receptors for immunoglobulin G: key elements in the pathogenesis of rheumatic disease

21 January 2018

1 reference

Antigen receptor tail clue.

21 January 2018

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21 January 2018

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Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4.

21 January 2018

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Molecular versatility of antibodies

21 January 2018

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Molecular adapters in Fc(epsilon)RI signaling and the allergic response

21 January 2018

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Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

21 January 2018

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Interactions of integrins with their partner proteins in leukocyte membranes.

21 January 2018

1 reference

Mac-1 (CD11b/CD18) as accessory molecule for Fc alpha R (CD89) binding of IgA.

21 January 2018

1 reference

Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG.

21 January 2018

1 reference

The IgG binding site of human FcgammaRIIIB receptor involves CC' and FG loops of the membrane-proximal domain

21 January 2018

1 reference

Localisation of the monocyte-binding region on human immunoglobulin G.

21 January 2018

1 reference

Localization of the binding site for the human high-affinity Fc receptor on IgG.

21 January 2018

1 reference

Fine Structure Analysis of Interaction of FcεRI with IgE

21 January 2018

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The structural basis of human IgE-Fc receptor interactions

21 January 2018

1 reference

Identification of residues in the CH2/CH3 domain interface of IgA essential for interaction with the human fcalpha receptor (FcalphaR) CD89

21 January 2018

1 reference

Immunoglobulin-binding sites of human FcalphaRI (CD89) and bovine Fcgamma2R are located in their membrane-distal extracellular domains

21 January 2018

1 reference

Bivalent binding of IgA1 to FcalphaRI suggests a mechanism for cytokine activation of IgA phagocytosis

21 January 2018

1 reference

Limited role of charge matching in the interaction of human immunoglobulin A with the immunoglobulin A Fc receptor (Fc alpha RI) CD89.

21 January 2018

1 reference

The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fcα receptor interactions

21 January 2018

1 reference

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

21 January 2018

1 reference

Streptococcal IgA-binding Proteins Bind in the Cα2-Cα3 Interdomain Region and Inhibit Binding of IgA to Human CD89

21 January 2018

1 reference

Immunoglobulin G: functional sites

21 January 2018

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

21 January 2018

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The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

21 January 2018

1 reference

Interaction of human IgG chimeric antibodies with the human FcRI and FcRII receptors: requirements for antibody-mediated host cell-target cell interaction

21 January 2018

1 reference

Antibody: the flexible adaptor molecule

21 January 2018

1 reference

Tandem duplication of rab genes followed by sequence divergence and acquisition of distinct functions in Trypanosoma brucei

21 January 2018

1 reference

Fc(epsilon)RI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells

21 January 2018

1 reference

The clustered Fcgamma receptor II is recruited to Lyn-containing membrane domains and undergoes phosphorylation in a cholesterol-dependent manner.

21 January 2018

1 reference

Association of FcgammaRII with low-density detergent-resistant membranes is important for cross-linking-dependent initiation of the tyrosine phosphorylation pathway and superoxide generation

21 January 2018

1 reference

IgA Fc receptor (FcalphaR) cross-linking recruits tyrosine kinases, phosphoinositide kinases and serine/threonine kinases to glycolipid rafts

21 January 2018

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Human antibodies as next generation therapeutics

21 January 2018

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Therapeutic antibodies for human diseases at the dawn of the twenty-first century

21 January 2018

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Recombinant immunoglobulin A: powerful tools for fundamental and applied research

21 January 2018

1 reference

Participation of the N-Terminal Region of Cε3 in the Binding of Human IgE to Its High-Affinity Receptor FcεRI

21 January 2018

1 reference

Crystallographic structure studies of an IgG molecule and an Fc fragment

21 January 2018

1 reference

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

31 March 2020

1 reference

Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains

31 March 2020

1 reference

A model for the solution conformation of rat IgE

31 March 2020

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Conformations of IgE bound to its receptor Fc epsilon RI and in solution

31 March 2020

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Further studies on the ultrastructure of dimeric IgA of human origin

31 March 2020

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Electron microscope examination of free IgA molecules and of their complexes with antigen

31 March 2020

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Electron microscopy of human and mouse myeloma serum IgA

31 March 2020

1 reference

Dynamic conformations compared for IgE and IgG1 in solution and bound to receptors

31 March 2020

1 reference

The gene for the human IgA Fc receptor maps to 19q13.4

31 March 2020

1 reference

Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation

31 March 2020

1 reference

Crystal structure of the extracellular domain of a human Fc gamma RIII

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Crystal structure of the human high-affinity IgE receptor

1 reference

Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)

31 March 2020

1 reference

Identification of the Fc gamma receptor class I binding site in human IgG through the use of recombinant IgG1/IgG2 hybrid and point-mutated antibodies

31 March 2020

1 reference

The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region

31 March 2020

1 reference

A conformational rearrangement upon binding of IgE to its high affinity receptor

31 March 2020

1 reference

Interaction of human IgE with Fc epsilon RI alpha exposes hidden epitopes on IgE

31 March 2020

1 reference

Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1

31 March 2020

1 reference

The interaction of Fc alpha RI with IgA and its implications for ligand binding by immunoreceptors of the leukocyte receptor cluster

31 March 2020

1 reference

Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG

31 March 2020

1 reference

Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction

31 March 2020

1 reference

Is IgM-like dislocation a common feature of antibody function?

31 March 2020

1 reference

Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains

31 March 2020

1 reference

Engineering antibodies for therapy

31 March 2020

1 reference

Three-dimensional structure of an intact human immunoglobulin

31 March 2020

1 reference

Three-dimensional structure of a human immunoglobulin with a hinge deletion

31 March 2020

1 reference

Human antibody effector function

31 March 2020

1 reference