Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1 (Q28248333)

https://api.crossref.org/works/10.1074%2FJBC.M603566200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Growing roles for the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Protein synthesis initiation factor 4G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Identification of a conserved motif required for mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

The Mammalian Target of Rapamycin Phosphorylates Sites Having a (Ser/Thr)-Pro Motif and Is Activated by Antibodies to a Region near Its COOH Terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Immunopharmacology of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Drosophila target of rapamycin kinase functions as a multimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Molecular organization of target of rapamycin complex 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Rheb binds and regulates the mTOR kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603566200

21 January 2018

Identifiers

DOI

10.1074/JBC.M603566200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16798736

1 reference

Consolidated OpenCitations Corpus – April 2017