Site‐specific recombinases: from tag‐and‐target‐ to tag‐and‐exchange‐based genomic modifications (Q28247128)

11 December 2024

main subject

genetic recombination

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21891781

Europe PubMed Central

PubMed publication ID

21891781

reference URL

11 December 2024

author name string

Soeren Turan

series ordinal

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Juergen Bode

series ordinal

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language of work or name

English

0 references

publication date

December 2011

0 references

2 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21891781

Europe PubMed Central

PubMed publication ID

21891781

reference URL

full work available at URL

11 December 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.11-186940

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

https://onlinelibrary.wiley.com/doi/full-xml/10.1096/fj.11-186940

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

11 December 2024

0 references

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4088-107

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cites work

Performance of genomic bordering elements at predefined genomic loci

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High-level transgene expression by homologous recombination-mediated gene transfer

11 December 2024

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Novel tag-and-exchange (RMCE) strategies generate master cell clones with predictable and stable transgene expression properties

11 December 2024

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Production of Non Viral DNA Vectors

11 December 2024

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Minicircle performance depending on S/MAR-nuclear matrix interactions

11 December 2024

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

11 December 2024

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Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease

11 December 2024

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Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy

11 December 2024

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DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

11 December 2024

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In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette

11 December 2024

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Multiplexing RMCE: versatile extensions of the Flp-recombinase-mediated cassette-exchange technology

11 December 2024

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Site-specific DNA recombinases as instruments for genomic surgery

11 December 2024

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Suicide substrates reveal properties of the homology-dependent steps during integrative recombination of bacteriophage lambda.

11 December 2024

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Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges

11 December 2024

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Comparative kinetic analysis of FLP and cre recombinases: mathematical models for DNA binding and recombination.

11 December 2024

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Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes

11 December 2024

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Mechanisms of site-specific recombination.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.

11 December 2024

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https://api.crossref.org/works/10.1096/FJ.11-186940

Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci

11 December 2024

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Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay

11 December 2024

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Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

11 December 2024

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Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase

11 December 2024

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Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange

11 December 2024

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A conditional allele at the mouse channel activating protease 1 (Prss8) gene locus.

11 December 2024

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Activity of yeast FLP recombinase in maize and rice protoplasts

11 December 2024

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Dynamic, structural, and regulatory aspects of lambda site-specific recombination

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange

11 December 2024

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Phage TP901-1 site-specific integrase functions in human cells

11 December 2024

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Site-specific recombination by phiC31 integrase and other large serine recombinases.

11 December 2024

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A phage protein that binds φC31 integrase to switch its directionality

11 December 2024

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Preliminary study on the DNA-binding properties of phage ΦC31 integrase

11 December 2024

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Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase

11 December 2024

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Highly efficient in vitro site-specific recombination system based on streptomyces phage phiBT1 integrase

11 December 2024

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Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity

11 December 2024

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Cellular restriction of retrovirus particle-mediated mRNA transfer

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Gammaretroviral vectors: biology, technology and application

11 December 2024

1 reference

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Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Protein transduction from retroviral Gag precursors

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Dual RMCE for efficient re-engineering of mouse mutant alleles

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

PhiC31 integrase facilitates genetic approaches combining multiple recombinases

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

High efficiency of a sequential recombinase-mediated cassette exchange reaction in Escherichia coli

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Arm site independence of coliphage HK022 integrase in human cells

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

VCre/VloxP and SCre/SloxP: new site-specific recombination systems for genome engineering

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Directed evolution of a recombinase for improved genomic integration at a native human sequence

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Integration specificity of phage phiC31 integrase in the human genome

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

A diversity of serine phage integrases mediate site-specific recombination in mammalian cells

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Therapeutic Applications of the PhiC31 Integrase System

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Long-term phenotypic correction in factor IX knockout mice by using phiC31 integrase-mediated gene therapy

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Mutational analysis of loxP sites for efficient Cre-mediated insertion into genomic DNA.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

HIV-1 proviral DNA excision using an evolved recombinase

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

A Genome-Wide Analysis of FRT-Like Sequences in the Human Genome

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Generation of a Series of Knock-In Alleles Using RMCE in ES Cells

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specificTrp53platform

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

The effect of chromosomal position on the expression of the Drosophila xanthine dehydrogenase gene.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Refinement of tools for targeted gene expression in Drosophila.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

High throughput gene trapping and postinsertional modifications of gene trap alleles.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

https://api.crossref.org/works/10.1096/FJ.11-186940

11 December 2024

From a dream to reality

1 reference

Resources for proteomics in mouse embryonic stem cells.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Synthesis of programmable integrases

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Non-integrative lentivirus drives high-frequency cre-mediated cassette exchange in human cells

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Anatomy of highly expressing chromosomal sites targeted by retroviral vectors

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

DNA binding and synapsis by the large C-terminal domain of phiC31 integrase.

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Intermediates in serine recombinase-mediated site-specific recombination

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site

11 December 2024

1 reference

https://api.crossref.org/works/10.1096/FJ.11-186940

11 December 2024

Identifiers

DOI

10.1096/FJ.11-186940

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

21891781

1 reference

Consolidated OpenCitations Corpus – April 2017