6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27 (Q28244084)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25032860%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27 (English)

1 reference

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9 March 2020

1 reference

1 reference

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9 March 2020

B F Clem

1 reference

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9 March 2020

Y Imbert-Fernandez

1 reference

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9 March 2020

S C Ozcan

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9 March 2020

S Peker

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9 March 2020

J O'Neal

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9 March 2020

A C Klarer

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9 March 2020

A L Clem

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9 March 2020

S Telang

1 reference

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9 March 2020

J Chesney

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9 March 2020

language of work or name

English

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publication date

17 July 2014

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9 March 2020

published in

Cell Death and Disease

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9 March 2020

volume

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9 March 2020

issue

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page(s)

e1337

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

9 March 2020

start time

1 July 2014

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases

20 March 2017

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20 March 2017

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6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

20 March 2017

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High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

20 March 2017

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20 March 2017

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20 March 2017

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Characterization of a Human Placental Fructose-6-Phosphate, 2-Kinase/Fructose- 2,6 - Bisphosphatase

20 March 2017

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

20 March 2017

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Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

20 March 2017

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Overexpression of fructose 2,6-bisphosphatase decreases glycolysis and delays cell cycle progression

20 March 2017

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Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3: Figure 1

20 March 2017

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Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells.

6 April 2017

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Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

29 September 2017

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E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

29 September 2017

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Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

29 September 2017

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CDK inhibitors: cell cycle regulators and beyond

29 September 2017

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Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation

29 September 2017

1 reference

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Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

29 September 2017

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p27Kip1 metabolism: a fascinating labyrinth

29 September 2017

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Another piece of the p27Kip1 puzzle

29 September 2017

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Ras transformation requires metabolic control by 6-phosphofructo-2-kinase

29 September 2017

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p27 as a target for cancer therapeutics

29 September 2017

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An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect

29 September 2017

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

29 September 2017

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Systemic elevation of PTEN induces a tumor-suppressive metabolic state

29 September 2017

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PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells

2 June 2018

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https://api.crossref.org/works/10.1038%2FCDDIS.2014.292

Increase in Fru-2,6-P(2) levels results in altered cell division in Schizosaccharomyces pombe

21 January 2018

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Cdc2-cyclin E complexes regulate the G1/S phase transition

21 January 2018

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The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

21 January 2018

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A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25032860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p27Kip1 overexpression causes apoptotic death of mammalian cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25032860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.292

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25032860%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25032860%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

25032860

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25032860%20AND%20SRC:MED&resulttype=core&format=json