The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells (Q28237020)

PAX interacting (with transcription-activation domain) protein 1

GOA release 2020-03-11

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GOA release 2020-03-11

Tagoh H

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Meinrad Busslinger

object named as

Busslinger M

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author name string

Shane McManus

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Anja Ebert

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Giorgia Salvagiotto

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Jasna Medvedovic

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Qiong Sun

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Ido Tamir

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Markus Jaritz

Histone modifications at human enhancers reflect global cell-type-specific gene expression

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language of work or name

English

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publication date

6 May 2011

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2388-404

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

An extended transcriptional network for pluripotency of embryonic stem cells

20 March 2017

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The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Genome regulation by polycomb and trithorax proteins

20 March 2017

1 reference

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

20 March 2017

1 reference

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Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

20 March 2017

1 reference

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A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription

20 March 2017

1 reference

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Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice

20 March 2017

1 reference

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The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins

20 March 2017

1 reference

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

20 March 2017

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Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Polycomb complexes repress developmental regulators in murine embryonic stem cells

20 March 2017

1 reference

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

7 April 2017

1 reference

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A high-resolution map of active promoters in the human genome

7 April 2017

1 reference

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Genomic maps and comparative analysis of histone modifications in human and mouse

7 April 2017

1 reference

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A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

29 September 2017

1 reference

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Chromatin remodelling during development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Deconstructing repression: evolving models of co-repressor action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Shifting players and paradigms in cell-specific transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Pax5: the guardian of B cell identity and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Transcriptional networks in developing and mature B cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Ligand control of coregulator recruitment to nuclear receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Reversion of B cell commitment upon loss of Pax5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Identification of Pax5 target genes in early B cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.140

Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116275

27 November 2018

Identifiers

DOI

10.1038/EMBOJ.2011.140

1 reference

1 reference

1 reference

PubMed publication ID

21552207

1 reference