Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations (Q28235418)

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scientific article (publication date: April 2009)

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English	Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations	scientific article (publication date: April 2009)

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instance of

scholarly article

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title

Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations (English)

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main subject

infectious disease

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author

Mark Wainberg

series ordinal

6

object named as

Mark A Wainberg

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Maureen Oliveira

series ordinal

1

object named as

Maureen Oliveira

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Bluma Brenner

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5

object named as

Bluma G Brenner

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Daniela Moisi

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2

object named as

Daniela Moisi

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author name string

Bonnie Spira

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3

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Susan Cox

series ordinal

4

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language of work or name

English

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publication date

April 2009

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published in

Antimicrobial Agents and Chemotherapy

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volume

53

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issue

4

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page(s)

1683-5

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cites work

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Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89

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20 March 2017

Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years

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20 March 2017

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase

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20 March 2017

Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine

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20 March 2017

The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations

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29 September 2017

In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection

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29 September 2017

Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture

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29 September 2017

K65R with and without S68: a new resistance profile in vivo detected in most patients failing abacavir, didanosine and stavudine

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29 September 2017

A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation

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Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].

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29 September 2017

Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine.

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The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation

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In vitro activity of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor (NRTI), against 215 HIV-1 isolates resistant to other NRTIs

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27 November 2018

Broad Nucleoside Reverse‐Transcriptase Inhibitor Cross‐Resistance in Human Immunodeficiency Virus Type 1 Clinical Isolates

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Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group

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27 November 2018

In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA.

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27 November 2018

Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex.

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27 November 2018

Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC).

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27 November 2018

Identifiers

DOI

10.1128/AAC.01168-08

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PMC publication ID

2663123

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PubMed publication ID

19223637

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ResearchGate publication ID

24021618

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