Signals from Eph and ephrin proteins: a developmental tool kit (Q28210262)

23 March 2017

author name string

A W Boyd

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M Lackmann

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A. W. Boyd

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23 March 2017

M. Lackmann

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23 March 2017

language of work or name

English

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publication date

11 December 2001

1 reference

Science's STKE : signal transduction knowledge environment

23 March 2017

published in

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Science Signaling

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23 March 2017

volume

2001

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23 March 2017

issue

112

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23 March 2017

page(s)

re20

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re20-re20

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A coherent nomenclature for Eph receptors and their ligands

23 March 2017

cites work

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Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization

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An early developmental role for eph-ephrin interaction during vertebrate gastrulation

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Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

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The ephrins and Eph receptors in neural development

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Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

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Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor

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Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

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The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif

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Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction

21 April 2017

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The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals

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Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

21 April 2017

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Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

21 April 2017

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Roles of Eph receptors and ephrins in segmental patterning

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Expression of Eph receptors in skeletal muscle and their localization at the neuromuscular junction

21 April 2017

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Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor

21 April 2017

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Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase

21 April 2017

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Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

21 April 2017

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A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A

21 April 2017

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An Eph receptor regulates integrin activity through R-Ras

21 April 2017

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Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

21 April 2017

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Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

21 April 2017

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Regulated cleavage of a contact-mediated axon repellent

21 April 2017

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The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner

21 April 2017

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Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity

21 April 2017

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Phosphorylation at Tyr-838 in the kinase domain of EphA8 modulates Fyn binding to the Tyr-615 site by enhancing tyrosine kinase activity

21 April 2017

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The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans

21 April 2017

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21 April 2017

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The ephrin VAB-2/EFN-1 functions in neuronal signaling to regulate epidermal morphogenesis in C. elegans

21 April 2017

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EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

21 April 2017

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21 April 2017

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Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control

21 April 2017

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21 April 2017

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Regulation of repulsion versus adhesion by different splice forms of an Eph receptor

21 April 2017

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21 April 2017

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Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

21 April 2017

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21 April 2017

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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

21 April 2017

2 references

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21 April 2017

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Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

21 April 2017

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Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/STKE.2001.112.RE20

Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/STKE.2001.112.RE20

Multiple roles of EPH receptors and ephrins in neural development

21 April 2017

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https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Excitatory Eph receptors and adhesive ephrin ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

An ephrin-A-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120-kDa protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Bidirectional signals establish boundaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Eph receptors and ephrins restrict cell intermingling and communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Signaling downstream of Eph receptors and ephrin ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Disruption of cell adhesion in Xenopus embryos by Pagliaccio, an Eph-class receptor tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Multiple ephrins control cell organization in C. elegans using kinase-dependent and -independent functions of the VAB-1 Eph receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

Development and reorganization of corticospinal projections in EphA4 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.112.RE20

10.1126/SCISIGNAL.1122001RE20

21 January 2018

Identifiers

DOI

0 references

10.1126/STKE.2001.112.RE20

1 reference