Discovery of new human beta-defensins using a genomics-based approach (Q28202377)

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A Schudy

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R Linzmeier

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J M Guthmiller

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G K Johnson

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B F Tack

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J P Mitros

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A Rosenthal

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P B McCray

Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung

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language of work or name

English

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publication date

24 January 2001

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published in

Gene

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volume

263

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issue

1-2

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page(s)

211-8

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Human enteric defensin genes: chromosomal map position and a model for possible evolutionary relationships

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A peptide antibiotic from human skin

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Antimicrobial peptides as mediators of epithelial host defense

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High-resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in ffttle standard karyotypes

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A novel murine beta -defensin expressed in tongue, esophagus, and trachea

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Cloning and analysis of mRNAs expressed specifically in the human epididymis

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Region-specific variation of gene expression in the human epididymis as revealed by in situ hybridization with tissue-specific cDNAs

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A 450-kb contig of defensin genes on human chromosome 8p23.

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Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation

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The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry

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The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa

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Human airway epithelia express a beta-defensin

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Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis

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Localization of the cryptdin locus on mouse chromosome 8.

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Production of beta-defensins by human airway epithelia

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Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

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