The endothelin axis: emerging role in cancer (Q28206793)

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Anna Bagnato

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Bruno Battistini

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Perry Nisen

Endothelins in health and disease: an overview

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language of work or name

English

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publication date

February 2003

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published in

Nature Reviews Cancer

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volume

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issue

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page(s)

110-6

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cites work

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Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)

21 January 2018

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Growth regulatory properties of endothelins

21 January 2018

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New therapeutics that antagonize endothelin: promises and frustrations

21 January 2018

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Endothelium-derived factors as paracrine mediators of prostate cancer progression

21 January 2018

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Endothelins and endothelin receptor antagonists: therapeutic considerations for a novel class of cardiovascular drugs

21 January 2018

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Endothelin receptor antagonists: current status and perspectives

21 January 2018

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

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Endothelin attenuates apoptosis in human smooth muscle cells

21 January 2018

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New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

21 January 2018

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Factors regulating the growth of metastatic cancer in bone

21 January 2018

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Metastasis to bone: causes, consequences and therapeutic opportunities

21 January 2018

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Molecular mechanisms of osteolytic bone metastases

21 January 2018

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Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption

21 January 2018

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Role of endothelin-1 in neovascularization of ovarian carcinoma

21 January 2018

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Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

21 January 2018

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Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.

21 January 2018

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Endothelin-1 promotes proteolytic activity of ovarian carcinoma

21 January 2018

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Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

21 January 2018

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Endothelin expression and responsiveness in human ovarian carcinoma cell lines

21 January 2018

1 reference

Paracrine regulation of ovarian cancer by endothelin

21 January 2018

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Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

21 January 2018

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Detection of endothelin immunoreactivity and mRNA in pulmonary tumours

21 January 2018

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Modulation of human colon tumor-stromal interactions by the endothelin system.

21 January 2018

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Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET(A) receptor antagonism

21 January 2018

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Expression of endothelin 1 and endothelin A receptor in HPV-associated cervical carcinoma: new potential targets for anticancer therapy

21 January 2018

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Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth

21 January 2018

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Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707.

21 January 2018

1 reference

Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics

21 January 2018

1 reference

ABT-627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro

21 January 2018

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Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells

21 January 2018

1 reference

An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

21 January 2018

1 reference

The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators

21 January 2018

1 reference

Decreased ET(B) receptor expression in human metastatic melanoma cells

21 January 2018

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Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes

21 January 2018

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Expression of the endothelin-B receptor in pigment cell lesions of the skin. Evidence for its role as tumor progression marker in malignant melanoma

21 January 2018

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A selective endothelin ETA antagonist, BQ-123, inhibits 125I-endothelin-1 (125I-ET-1) binding to human meningiomas and antagonizes ET-1-induced proliferation of meningioma cells

21 January 2018

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21 January 2018

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Endothelin-1 production and agonist activities in cultured prostate-derived cells: implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia

31 March 2020

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The endothelin family: an overview

31 March 2020

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Endothelins as autocrine regulators of tumor cell growth

31 March 2020

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Regulation of apoptosis by vasoactive peptides

31 March 2020

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Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells

31 March 2020

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Endothelin receptor blockade potentiates FasL-induced apoptosis in colon carcinoma cells via the protein kinase C-pathway

31 March 2020

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Endothelin receptor blockade potentiates FasL-induced apoptosis in rat colon carcinoma cells

31 March 2020

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Endothelins are angiogenic

31 March 2020

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Expression of endothelin receptor a associated with prostate cancer progression

31 March 2020

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New drug slows prostate-cancer progression

31 March 2020

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Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial

31 March 2020

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Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium

31 March 2020

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Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression

31 March 2020

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Augmented expression of endothelin-1, endothelin-3 and the endothelin-B receptor in breast carcinoma

31 March 2020

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Human melanoma cells express functional endothelin-1 receptors

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC990

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1013244158

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Fatcat ID

release_mvbbdncxhbhbhdjktoesm4dfgy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mvbbdncxhbhbhdjktoesm4dfgy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12563310

1 reference

Consolidated OpenCitations Corpus – April 2017