The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1 (Q28186148)

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21 December 2019

title

The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1 (English)

1 reference

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21 December 2019

main subject

squamous cell carcinoma

1 reference

1 reference

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21 December 2019

Yasuhisa Sakata

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21 December 2019

Toshiro Takai

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21 December 2019

Wataru Sakurai

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21 December 2019

Kiyonari Masumoto

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21 December 2019

Noriko Yuyama

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21 December 2019

Yoshinori Suminami

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21 December 2019

Fumio Kishi

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21 December 2019

Tetsuji Yamashita

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21 December 2019

Takeshi Kato

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21 December 2019

Hideoki Ogawa

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21 December 2019

Kazuma Fujimoto

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21 December 2019

Yo Matsuo

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21 December 2019

Yuji Sugita

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21 December 2019

Kenji Izuhara

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21 December 2019

language of work or name

English

0 references

publication date

20 November 2003

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Journal of Biological Chemistry

21 December 2019

published in

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21 December 2019

volume

279

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21 December 2019

issue

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21 December 2019

page(s)

5081-5087

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Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase

21 December 2019

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A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene

21 January 2018

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Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma

21 January 2018

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Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas

21 January 2018

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Squamous cell carcinoma antigen is a potent inhibitor of cysteine proteinase cathepsin L.

21 January 2018

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Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

21 January 2018

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Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

21 January 2018

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Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

21 January 2018

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Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

21 January 2018

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Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A.

21 January 2018

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The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

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Analysis of novel disease-related genes in bronchial asthma

21 January 2018

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IL-12/IL-13 axis in allergic asthma

21 January 2018

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Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.

21 January 2018

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A mite subversive: cleavage of CD23 and CD25 by Der p 1 enhances allergenicity

21 January 2018

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Comparative modelling of major house dust mite allergen Der p I: structure validation using an extended environmental amino acid propensity table

21 January 2018

1 reference

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Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

21 January 2018

1 reference

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House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.

21 January 2018

1 reference

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A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases

21 January 2018

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Proteolytic Cleavage of CD25, the α Subunit of the Human T Cell Interleukin 2 Receptor, by Der p 1, a Major Mite Allergen with Cysteine Protease Activity

21 January 2018

1 reference

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The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level

21 January 2018

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Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1

21 January 2018

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Biologically active recombinant forms of a major house dust mite group 1 allergen Der f 1 with full activities of both cysteine protease and IgE binding

21 January 2018

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Maturation of the activities of recombinant mite allergens Der p 1 and Der f 1, and its implication in the blockade of proteolytic activity

21 January 2018

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A sensitive fluorescent assay for measuring the cysteine protease activity of Der p 1, a major allergen from the dust mite Dermatophagoides pteronyssinus

21 January 2018

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Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

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Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

21 January 2018

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The other side of the coin: the protective role of the TH2 cytokines.

21 January 2018

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Serpins and other covalent protease inhibitors

21 January 2018

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Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

21 January 2018

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Ultrastructural and immunohistochemical evidence for release of eosinophilic granules in vivo: cytotoxic potential in chronic eosinophilic pneumonia

21 January 2018

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Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study

21 January 2018

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Quantitative assessments of IgG and IgE antibodies to inhalant allergens in patients with atopic dermatitis

21 January 2018

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The allergen Der p1 induces NF-kappaB activation through interference with IkappaB alpha function in asthmatic bronchial epithelial cells

21 January 2018

1 reference

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Functional effects of the inhibition of the cysteine protease activity of the major house dust mite allergen Der p 1 by a novel peptide-based inhibitor

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M311585200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630915%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

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