The role of colonic bacteria in the metabolism of the natural isoflavone daidzin to equol (Q28087603)

Creative Commons Attribution 4.0 International

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14 January 2015

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April 2022 Public Data File from Crossref

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cites work

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R(-)-O-desmethylangolensin is the main enantiomeric form of daidzein metabolite produced by human in vitro and in vivo.

29 September 2017

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Soy isoflavones and prostate cancer: a review of molecular mechanisms

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The effects of dietary treatment with S-equol on learning and memory processes in middle-aged ovariectomized rats

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Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens

29 September 2017

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Isolation and characterization of novel S-equol-producing bacteria from brines of stinky tofu, a traditional fermented soy food in Taiwan

29 September 2017

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Isoflavone metabolism and bone-sparing effects of daidzein-metabolites

29 September 2017

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Daidzein, R-(+)equol and S-(-)equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2.

29 September 2017

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Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens

29 September 2017

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Impact of dose, frequency of administration, and equol production on efficacy of isoflavones for menopausal hot flashes: a pilot randomized trial

29 September 2017

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Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments

29 September 2017

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Beneficial effects of phytoestrogens and their metabolites produced by intestinal microflora on bone health

29 September 2017

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Endogenous and exogenous equol are antiestrogenic in reproductive tissues of apolipoprotein e-null mice

29 September 2017

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Identification of a novel dihydrodaidzein racemase essential for biosynthesis of equol from daidzein in Lactococcus sp. strain 20-92.

29 September 2017

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Identification of an enzyme system for daidzein-to-equol conversion in Slackia sp. strain NATTS.

29 September 2017

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Equol production changes over time in pre-menopausal women

29 September 2017

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Complete genomic sequence of the equol-producing bacterium Eggerthella sp. strain YY7918, isolated from adult human intestine

29 September 2017

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Ageing skin: oestrogen receptor β agonists offer an approach to change the outcome

29 September 2017

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Equol an isoflavonoid: potential for improved prostate health, in vitro and in vivoevidence

29 September 2017

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Transcriptional activity of estrogen-related receptor γ (ERRγ) is stimulated by the phytoestrogen equol

29 September 2017

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Cloning and expression of a novel NADP(H)-dependent daidzein reductase, an enzyme involved in the metabolism of daidzein, from equol-producing Lactococcus strain 20-92.

29 September 2017

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Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient

29 September 2017

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The pharmacokinetics of S-(-)equol administered as SE5-OH tablets to healthy postmenopausal women

29 September 2017

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Slackia equolifaciens sp. nov., a human intestinal bacterium capable of producing equol

29 September 2017

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Stereospecific biotransformation of dihydrodaidzein into (3S)-equol by the human intestinal bacterium Eggerthella strain Julong 732.

29 September 2017

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Asaccharobacter celatus gen. nov., sp. nov., isolated from rat caecum

29 September 2017

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Adlercreutzia equolifaciens gen. nov., sp. nov., an equol-producing bacterium isolated from human faeces, and emended description of the genus Eggerthella

29 September 2017

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Estrogen signaling multiple pathways to impact gene transcription

29 September 2017

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Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women.

29 September 2017

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Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.

29 September 2017

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Metabolism of dietary soy isoflavones to equol by human intestinal microflora--implications for health

29 September 2017

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Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces

29 September 2017

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Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of Daidzein in cultured human Ishikawa cells

29 September 2017

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29 September 2017

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29 September 2017

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Phytoestrogens are potent inhibitors of estrogen sulfation: implications for breast cancer risk and treatment.

29 September 2017

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29 September 2017

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Soy isoflavones: a safety review

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The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones

29 September 2017

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Dietary isoflavones: biological effects and relevance to human health

29 September 2017

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Effects of the natural endocrine disruptor equol on the pituitary function in adult male rats

29 September 2017

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2 June 2018

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Metabolites of daidzein and genistein and their biological activities

2 June 2018

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Soya--a dietary source of the non-steroidal oestrogen equol in man and animals.

2 June 2018

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Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals

2 June 2018

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21 January 2018

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21 January 2018

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Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Estrogen receptor-mediated effects of isoflavone supplementation were not observed in whole-genome gene expression profiles of peripheral blood mononuclear cells in postmenopausal, equol-producing women.

21 January 2018

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Differential effects of dietary phyto-oestrogens daidzein and equol on human breast cancer MCF-7 cells

21 January 2018

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Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element

21 January 2018

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The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification

21 January 2018

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Soy isoflavones increase quinone reductase in hepa-1c1c7 cells via estrogen receptor beta and nuclear factor erythroid 2-related factor 2 binding to the antioxidant response element

21 January 2018

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Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitro

21 January 2018

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Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats

21 January 2018

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Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein.

21 January 2018

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Conversion of (3S,4R)-tetrahydrodaidzein to (3S)-equol by THD reductase: proposed mechanism involving a radical intermediate.

21 January 2018

1 reference

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Isolation and characterization of a novel equol-producing bacterium from human feces

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMETABO5010056

Discovery of an S-equol rich food stinky tofu, a traditional fermented soy product in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMETABO5010056

Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMETABO5010056

Daidzein and genistein are converted to equol and 5-hydroxy-equol by human intestinal Slackia isoflavoniconvertens in gnotobiotic rats.

21 January 2018

1 reference

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Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria

21 January 2018

1 reference

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Identification of two novel reductases involved in equol biosynthesis in Lactococcus strain 20-92.

21 January 2018

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Phenotypic typing, technological properties and safety aspects of Lactococcus garvieae strains from dairy environments.

21 January 2018

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Comparison of the effects of antimicrobial agents from three different classes on metabolism of isoflavonoids by colonic microflora using Etest strips

21 January 2018

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Biofluid 1H NMR-based metabonomic techniques in nutrition research - metabolic effects of dietary isoflavones in humans

21 January 2018

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Daidzein supplementation decreases serum triglyceride and uric acid concentrations in hypercholesterolemic adults with the effect on triglycerides being greater in those with the GA compared with the GG genotype of ESR-β RsaI.

21 January 2018

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Application of biofluid 1 H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile

21 January 2018

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The antioxidant activity of daidzein metabolites, O‑desmethylangolensin and equol, in HepG2 cells

21 January 2018

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Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms

27 November 2018

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Metabolic phenotype of isoflavones differ among female rats, pigs, monkeys, and women

27 November 2018

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Phytoestrogen concentrations in serum from Japanese men and women over forty years of age.

27 November 2018

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Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes

27 November 2018

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12 December 2020

Involvement of a soybean ATP-binding cassette-type transporter in the secretion of genistein, a signal flavonoid in legume-Rhizobium symbiosis

1 reference

12 December 2020

Antioxidant action and potential antidiabetic properties of an isoflavonoid-containing soyabean phytochemical extract (SPE)

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12 December 2020

The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial

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12 December 2020

In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production

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12 December 2020

The resident faecal flora is determined by genetic characteristics of the host. Implications for Crohn's disease?

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12 December 2020

Metabolism of daidzein and genistein by intestinal bacteria

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12 December 2020

In vitro bioassays of non-steroidal phytoestrogens

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12 December 2020

Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum

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12 December 2020

Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin

1 reference

12 December 2020

Antioxidant effect of a phytoestrogen equol on cultured muscle cells of embryonic broilers

1 reference

12 December 2020

Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men

1 reference

12 December 2020

A pilot study on the effects of S-equol compared to soy isoflavones on menopausal hot flash frequency

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12 December 2020

Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro

1 reference

12 December 2020

Is equol production beneficial to health?

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12 December 2020

Bioavailability of soybean isoflavones from aglycone and glucoside forms in American women

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12 December 2020

Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones

1 reference

12 December 2020

A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids

1 reference

12 December 2020

Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity

1 reference

12 December 2020

Hydrolysis of isoflavone glycosides to aglycones by beta-glycosidase does not alter plasma and urine isoflavone pharmacokinetics in postmenopausal women

1 reference

12 December 2020

Identifiers

DOI

10.3390/METABO5010056

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PubMed publication ID

25594250

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