SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function (Q28086933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

review article

1 reference

title

SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Chulbul M I Ahmed

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Howard M Johnson

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

1 reference

21 April 2015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

published in

Frontiers in Immunology

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

183

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

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20 March 2017

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SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

20 March 2017

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Signal Transduction and the Control of Gene Expression

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

20 March 2017

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Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1

20 March 2017

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Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance

20 March 2017

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Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor

20 March 2017

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SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

20 March 2017

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20 March 2017

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Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain

20 March 2017

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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

20 March 2017

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SOCS1 and regulation of regulatory T cells plasticity

29 September 2017

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Suppressor of cytokine signaling 1-derived peptide inhibits Janus kinase/signal transducers and activators of transcription pathway and improves inflammation and atherosclerosis in diabetic mice.

29 September 2017

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Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.

29 September 2017

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FOXP3 and scurfy: how it all began

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SOCS proteins in regulation of receptor tyrosine kinase signaling

29 September 2017

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Homeostatic control of regulatory T cell diversity.

29 September 2017

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The role of a non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis: An example of Occam's Broom?

29 September 2017

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Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

29 September 2017

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SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production

29 September 2017

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Inhibition of SOCS1-/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3+ regulatory T cell homeostasis

29 September 2017

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Cross-Talk between Programmed Death-1 and Suppressor of Cytokine Signaling-1 in Inhibition of IL-12 Production by Monocytes/Macrophages in Hepatitis C Virus Infection

29 September 2017

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The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis

29 September 2017

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Enhancement of antiviral immunity by small molecule antagonist of suppressor of cytokine signaling

29 September 2017

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Deficient SOCS3 and SHP-1 expression in psoriatic T cells

29 September 2017

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Knowns and unknowns in the future of multiple sclerosis treatment

29 September 2017

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HSV-1-induced SOCS-1 expression in keratinocytes: use of a SOCS-1 antagonist to block a novel mechanism of viral immune evasion

29 September 2017

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Linking folding and binding

29 September 2017

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Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes

29 September 2017

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SOCS regulation of the JAK/STAT signalling pathway

29 September 2017

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Interplay between pathogenic Th17 and regulatory T cells

29 September 2017

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29 September 2017

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Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: implications for the development of a SOCS-1 antagonist

29 September 2017

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The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

29 September 2017

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SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling

29 September 2017

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29 September 2017

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Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing

29 September 2017

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Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction

29 September 2017

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Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function

29 September 2017

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

29 September 2017

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Suppressors of cytokine signalling (SOCS) in the immune system

29 September 2017

1 reference

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SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

29 September 2017

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29 September 2017

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29 September 2017

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Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4.

29 September 2017

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Binding of peptides that are specified by complementary RNAs

2 June 2018

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2 June 2018

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27 November 2018

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27 November 2018

1 reference

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De novo design of peptides targeted to the EF hands of calmodulin.

27 November 2018

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Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25954276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads

1 reference

https://pubmed.ncbi.nlm.nih.gov/25954276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25954276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FIMMU.2015.00183

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25954276

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25954276%20AND%20SRC:MED&resulttype=core&format=json