Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae (Q27936292)

18156287

1 December 2016

title

Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae (English)

1 reference

18156287

DNA-binding transcriptional regulator UME6 YDR207C

1 December 2016

main subject

Saccharomyces cerevisiae

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1 reference

ORCID Public Data File 2021

GOA release 2020-03-11

Hongyuan Yang

1 reference

author name string

Weihua Fei

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Gabriel Alfaro

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Baby-Periyanayaki Muthusamy

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Zachary Klaassen

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Todd R Graham

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Christopher T Beh

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language of work or name

English

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publication date

February 2008

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1 reference

A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast.

1 December 2016

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401-14

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cites work

1 reference

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Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast

20 March 2017

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Diacylglycerol and its formation by phospholipase C regulate Rab- and SNARE-dependent yeast vacuole fusion

20 March 2017

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Role of Vma21p in assembly and transport of the yeast vacuolar ATPase

20 March 2017

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Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function

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A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution

20 March 2017

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Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae

20 March 2017

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The yeast vacuolar proton-translocating ATPase contains a subunit homologous to the Manduca sexta and bovine e subunits that is essential for function

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The CWH8 gene encodes a dolichyl pyrophosphate phosphatase with a luminally oriented active site in the endoplasmic reticulum of Saccharomyces cerevisiae

20 March 2017

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Overlapping functions of the yeast oxysterol-binding protein homologues.

20 March 2017

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Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.

20 March 2017

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A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast.

20 March 2017

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Role for Drs2p, a P-type ATPase and potential aminophospholipid translocase, in yeast late Golgi function

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The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation

20 March 2017

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An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae

20 March 2017

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KAR5 encodes a novel pheromone-inducible protein required for homotypic nuclear fusion

20 March 2017

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TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation

20 March 2017

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A two-component system that regulates an osmosensing MAP kinase cascade in yeast

20 March 2017

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The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

20 March 2017

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UME6 is a key regulator of nitrogen repression and meiotic development

20 March 2017

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Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex

20 March 2017

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Sterol methylation in Saccharomyces cerevisiae

20 March 2017

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Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase

20 March 2017

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The yeast SEC53 gene encodes phosphomannomutase.

20 March 2017

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

20 March 2017

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Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant

20 March 2017

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Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.

20 March 2017

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

20 March 2017

1 reference

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Systematic genetic analysis with ordered arrays of yeast deletion mutants

20 March 2017

1 reference

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Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2238164

Sterol esterification in yeast: a two-gene process

20 March 2017

1 reference

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Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes

20 March 2017

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant

7 April 2017

1 reference

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Synthesis, storage and degradation of neutral lipids in yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2238164

Intracellular sterol transport and distribution.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2238164

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

29 September 2017

1 reference

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Cell biology. A fungal Achilles' heel

29 September 2017

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A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides

29 September 2017

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Flippases and vesicle-mediated protein transport

29 September 2017

1 reference

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Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum

29 September 2017

1 reference

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Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

29 September 2017

1 reference

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Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

29 September 2017

1 reference

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Triacylglycerol biosynthesis in yeast

29 September 2017

1 reference

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Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2238164

Cholesterol trafficking in the secretory and endocytic systems

29 September 2017

1 reference

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Calcineurin is essential for survival during membrane stress in Candida albicans

29 September 2017

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Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast

29 September 2017

1 reference

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Intracellular lipid particles of eukaryotic cells

29 September 2017

1 reference

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Transcriptional regulation of meiosis in yeast

29 September 2017

1 reference

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mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response

29 September 2017

1 reference

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Synthetic genetic interactions with temperature-sensitive clathrin in Saccharomyces cerevisiae. Roles for synaptojanin-like Inp53p and dynamin-related Vps1p in clathrin-dependent protein sorting at the trans-Golgi network

29 September 2017

1 reference

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Intracellular cholesterol transport.

29 September 2017

1 reference

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Mechanisms of lipid-body formation

29 September 2017

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Role of UME6 in Transcriptional Regulation of a DNA Repair Gene in Saccharomyces cerevisiae

29 September 2017

1 reference

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Ca2+-calmodulin promotes survival of pheromone-induced growth arrest by activation of calcineurin and Ca2+-calmodulin-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2238164

Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism

29 September 2017

1 reference

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The upstream region of the FOX3 gene encoding peroxisomal 3-oxoacyl-coenzyme A thiolase in Saccharomyces cerevisiae contains ABF1- and replication protein A-binding sites that participate in its regulation by glucose repression

29 September 2017

1 reference

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Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent

29 September 2017

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Nystatin-Resistant Mutants of Yeast: Alterations in Sterol Content

29 September 2017

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Changes in the lipid composition and fine structure of Saccharomyces cerevisiae during ascus formation

29 September 2017

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Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast

29 September 2017

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Antibodies to nystatin demonstrate polyene sterol specificity and allow immunolabeling of sterols in Saccharomyces cerevisiae

29 September 2017

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Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling

29 September 2017

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Cholesterol cytochemistry in cell biology and disease

2 June 2018

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Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

2 June 2018

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The N-glycosylation defect of cwh8Delta yeast cells causes a distinct defect in sphingolipid biosynthesis

27 November 2018

1 reference

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A yeast strain lacking lipid particles bears a defect in ergosterol formation

27 November 2018

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Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast

27 November 2018

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Evidence for antagonistic regulation of cell growth by the calcineurin and high osmolarity glycerol pathways in Saccharomyces cerevisiae

27 November 2018

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SCAP, an ER sensor that regulates cell cholesterol

27 November 2018

1 reference

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Storage lipid synthesis is non-essential in yeast.

27 November 2018

1 reference

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Sphingomyelinase enhances low density lipoprotein uptake and ability to induce cholesteryl ester accumulation in macrophages

27 November 2018

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12 December 2020

Genetic evidence for the functional redundancy of the calcineurin- and Mpk1-mediated pathways in the regulation of cellular events important for growth in Saccharomyces cerevisiae

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12 December 2020

Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae

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12 December 2020

Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase

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12 December 2020

Intracellular cholesterol transport

1 reference

12 December 2020

Identifiers

DOI

10.1128/EC.00386-07

1 reference

1 reference

1 reference

18156287

1 reference