GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. (Q27865189)

16 November 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17395749%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17395749%20AND%20SRC:MED&resulttype=core&format=json

Free fatty acid receptor 1

28 December 2019

main subject

fatty acid

0 references

1 reference

GOA release 2020-03-11

1 reference

1 reference

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28 December 2019

1 reference

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28 December 2019

Thomas L Jetton

1 reference

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28 December 2019

Martin G Latour

1 reference

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28 December 2019

Jian Luo

1 reference

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28 December 2019

Elizabeth Oseid

1 reference

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28 December 2019

Daniel C-H Lin

1 reference

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28 December 2019

Caroline Tremblay

1 reference

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28 December 2019

language of work or name

English

0 references

publication date

1 April 2007

1 reference

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28 December 2019

2 references

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28 December 2019

volume

1 reference

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28 December 2019

issue

1 reference

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28 December 2019

page(s)

1087-1094

1 reference

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Role of GPR40 in fatty acid action on the beta cell line INS-1E.

28 December 2019

cites work

1 reference

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Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

A novel Galphaq/11-selective inhibitor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Progress in methodology. Improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Fatty acids, lipotoxicity and insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Stimulation of insulin secretion by infusion of free fatty acids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Mechanisms of compensatory beta-cell growth in insulin-resistant rats: roles of Akt kinase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

Effect on plasma free fatty acids on plasma glucagon and serum insulin concentrations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853382

27 November 2018

Identifiers

DOI

10.2337/DB06-1532

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17395749%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

2 references

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28 December 2019

PubMed publication ID

17395749

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17395749%20AND%20SRC:MED&resulttype=core&format=json