Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor (Q27730375)

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Mechanism of inhibition of 3α,20β-hydroxysteroid dehydrogenaseby a licorice-derived steroidal inhibitor

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English	Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor	scientific article	Mechanism of inhibition of 3α,20β-hydroxysteroid dehydrogenaseby a licorice-derived steroidal inhibitor

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scholarly article

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Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor (English)

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Mechanism of inhibition of 3α,20β-hydroxysteroid dehydrogenaseby a licorice-derived steroidal inhibitor (English)

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Zdzislaw Wawrzak

3

object named as

Zdzislaw Wawrzak

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author name string

D Ghosh

1

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M Erman

2

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Z Wawrzak

3

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W L Duax

4

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W Pangborn

5

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Debashis Ghosh

1

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Mary Erman

2

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William L Duax

4

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Walter Pangborn

5

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publication date

15 October 1994

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October 1994

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2

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10

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973-80

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973-980

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Structural features of ring A and the interaction of 20-oxosteroids with cortisone reductase

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Three-dimensional structure of holo 3 alpha,20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family

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The refined three-dimensional structure of 3 alpha,20 beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases

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Crystal structure of rat liver dihydropteridine reductase

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Site-specific mutagenesis of Drosophila alcohol dehydrogenase: evidence for involvement of tyrosine-152 and lysine-156 in catalysis

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Protein engineering of Drosophila alcohol dehydrogenase. The hydroxyl group of Tyr152 is involved in the active site of the enzyme.

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Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme

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Tyr-179 and Lys-183 are essential for enzymatic activity of 11β-hydroxysteroid dehydrogenase

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Bifunctional enzyme activity at the same active site: study of 3 alpha and 20 beta activity by affinity alkylation of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroids

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Licorice inhibits corticosteroid 11 beta-dehydrogenase of rat kidney and liver: in vivo and in vitro studies

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Characteristics of short-chain alcohol dehydrogenases and related enzymes

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A graphics model building and refinement system for macromolecules

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Conformation of Polypeptides and Proteins

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10.1016/S0969-2126(94)00099-9

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