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    title
    Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations (English)
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    Ted W Johnson
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    1
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    Paul F Richardson
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    2
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    Simon Bailey
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    3
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    Alexei Brooun
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    4
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    Benjamin J Burke
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    5
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    Michael R Collins
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    6
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    J Jean Cui
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    7
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    Judith G Deal
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    8
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    Ya-Li Deng
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    9
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    Dac Dinh
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    10
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    Lars D Engstrom
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    11
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    Mingying He
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    12
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    Jacqui Hoffman
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    13
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    Robert L Hoffman
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    14
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    Qinhua Huang
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    15
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    Robert S Kania
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    16
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    John C Kath
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    17
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    Hieu Lam
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    18
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    Justine L Lam
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    19
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    Phuong T Le
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    20
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    Laura Lingardo
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    21
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    Wei Liu
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    22
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    Michele McTigue
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    23
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    Cynthia L Palmer
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    24
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    Neal W Sach
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    25
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    Tod Smeal
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    26
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    Graham L Smith
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    27
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    Albert E Stewart
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    28
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    Sergei Timofeevski
    series ordinal
    29
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    Huichun Zhu
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    30
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    Jinjiang Zhu
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    31
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    Helen Y Zou
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    32
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    Martin P Edwards
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    33
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    publication date
    12 June 2014
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    volume
    57
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    issue
    11
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    page(s)
    4720-44
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