The role of distant mutations and allosteric regulation on LovD active site dynamics (Q27683292)

object named as

Sílvia Osuna

0 references

Kendall Houk

object named as

K N Houk

0 references

Gonzalo Jiménez-Osés

object named as

Gonzalo Jiménez-Osés

0 references

Michael R Sawaya

0 references

Todd O Yeates

0 references

Xue Gao

0 references

Lynne Gilson

0 references

Steven J Collier

0 references

Gjalt W Huisman

0 references

Yi Tang

Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis

0 references

language of work or name

1 reference

June 2014

0 references

published in

Nature Chemical Biology

0 references

volume

0 references

issue

0 references

page(s)

431-6

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Solution structure of an acyl carrier protein domain from a fungal type I polyketide synthase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Directed Evolution and Structural Characterization of a Simvastatin Synthase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

The RosettaDock server for local protein-protein docking

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Structure of fungal fatty acid synthase and implications for iterative substrate shuttling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

EstB from Burkholderia gladioli: A novel esterase with a β-lactamase fold reveals steric factors to discriminate between esterolytic and β-lactam cleaving activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Features and development of Coot

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Macromolecular TLS refinement in REFMAC at moderate resolutions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

VMD: visual molecular dynamics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Assessment of protein models with three-dimensional profiles

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

De Novo Enzyme Design Using Rosetta3

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Development and testing of a general amber force field

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Atomic-Level Characterization of the Structural Dynamics of Proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Improved protein-ligand docking using GOLD

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Verification of protein structures: patterns of nonbonded atomic interactions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

On the Dielectric "Constant" of Proteins: Smooth Dielectric Function for Macromolecular Modeling and Its Implementation in DelPhi

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Transitions to catalytically inactive conformations in EGFR kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Computational enzyme design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

How fast-folding proteins fold

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Achieving reliability and high accuracy in automated protein docking: ClusPro, PIPER, SDU, and stability analysis in CAPRI rounds 13-19

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Acyltransferase mediated polyketide release from a fungal megasynthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Gaussian split Ewald: A fast Ewald mesh method for molecular simulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

ClusPro: a fully automated algorithm for protein-protein docking

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

A perspective on enzyme catalysis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

What are the dielectric "constants" of proteins and how to validate electrostatic models?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Directed evolution of biocatalysts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Efficient synthesis of simvastatin by use of whole-cell biocatalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028369

Anton, a special-purpose machine for molecular dynamics simulation

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Improving catalytic function by ProSAR-driven enzyme evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other fun

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Continuous surface charge polarizable continuum models of solvation. I. General formalism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

PIPER: an FFT-based protein docking program with pairwise potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

ClusPro: an automated docking and discrimination method for the prediction of protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Reversible multiple time scale molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

The Geometry of the Ribosomal Polypeptide Exit Tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24727900

12 December 2020

inferred from PubMed ID database lookup

Architecture of mammalian fatty acid synthase at 4.5 A resolution

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24727900

12 December 2020

inferred from PubMed ID database lookup

Protein conformational disorder and enzyme catalysis

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

7 January 2021

inferred from DOI database lookup

A smooth particle mesh Ewald method

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1503

7 January 2021