Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a VH3-30-Encoded Heterosubtypic Antibody (Q27683187)

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Cyrille Dreyfus

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Ines Kohler

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Marco Steck

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Lars Hangartner

Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

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publication date

June 2014

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7083-92

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cites work

1 reference

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A common solution to group 2 influenza virus neutralization

20 March 2017

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Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

20 March 2017

1 reference

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New world bats harbor diverse influenza A viruses

20 March 2017

1 reference

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Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

20 March 2017

1 reference

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Structure of a Classical Broadly Neutralizing Stem Antibody in Complex with a Pandemic H2 Influenza Virus Hemagglutinin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity

20 March 2017

1 reference

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Cross-neutralization of influenza A viruses mediated by a single antibody loop

20 March 2017

1 reference

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Structural and genetic basis for development of broadly neutralizing influenza antibodies

20 March 2017

1 reference

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Highly Conserved Protective Epitopes on Influenza B Viruses

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

A highly conserved neutralizing epitope on group 2 influenza A viruses

20 March 2017

1 reference

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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

1 reference

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Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Antibody recognition of a highly conserved influenza virus epitope

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

20 March 2017

1 reference

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Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

20 March 2017

1 reference

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Human illness from avian influenza H7N3, British Columbia

20 March 2017

1 reference

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Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Features and development of Coot

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Solving structures of protein complexes by molecular replacement with Phaser

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Satisfying hydrogen bonding potential in proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Solvent-accessible surfaces of proteins and nucleic acids

20 March 2017

1 reference

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A DNA transfection system for generation of influenza A virus from eight plasmids

7 April 2017

1 reference

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Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs.

7 April 2017

1 reference

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Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.

29 September 2017

1 reference

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A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses

29 September 2017

1 reference

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A distinct lineage of influenza A virus from bats

29 September 2017

1 reference

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Naturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Localization of epitopes recognized by monoclonal antibodies that neutralized the H3N2 influenza viruses in man

29 September 2017

1 reference

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Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

29 September 2017

1 reference

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Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Scientific barriers to developing vaccines against avian influenza viruses.

29 September 2017

1 reference

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Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003.

29 September 2017

1 reference

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A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Seroevidence for H5N1 influenza infections in humans: meta-analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Antigenic structure of the haemagglutinin of human influenza A/H2N2 virus

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054347

Universal primer set for the full-length amplification of all influenza A viruses

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24719426