Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide (Q27682411)

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Pulkit Gupta

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Nora Vázquez-Laslop

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Alexander S Mankin

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Daniel N Wilson

Structural basis for TetM-mediated tetracycline resistance

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language of work or name

English

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publication date

24 March 2014

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published in

Nature Communications

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volume

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page(s)

3501

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cites work

1 reference

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Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

20 March 2017

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Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis

20 March 2017

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Structural insight into nascent polypeptide chain-mediated translational stalling.

20 March 2017

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Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

20 March 2017

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Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

20 March 2017

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Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

20 March 2017

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The structures of four macrolide antibiotics bound to the large ribosomal subunit

20 March 2017

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Structure of the 70S ribosome complexed with mRNA and tRNA

20 March 2017

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20 March 2017

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20 March 2017

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SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

20 March 2017

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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

20 March 2017

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Arrest peptides: cis-acting modulators of translation.

20 March 2017

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Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action

29 September 2017

1 reference

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Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

29 September 2017

1 reference

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SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center

29 September 2017

1 reference

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The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

29 September 2017

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A structural view on the mechanism of the ribosome-catalyzed peptide bond formation

29 September 2017

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Programmed drug-dependent ribosome stalling

29 September 2017

1 reference

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Translational attenuation and mRNA stabilization as mechanisms of erm(B) induction by erythromycin

29 September 2017

1 reference

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An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

29 September 2017

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Fitting of high-resolution structures into electron microscopy reconstruction images.

29 September 2017

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The ribosome as an entropy trap

29 September 2017

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Nonorthologous replacement of lysyl-tRNA synthetase prevents addition of lysine analogues to the genetic code

29 September 2017

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Induction of ermSV by 16-membered-ring macrolide antibiotics

29 September 2017

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Low resolution meets high: towards a resolution continuum from cells to atoms

29 September 2017

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A complex attenuator regulates inducible resistance to macrolides, lincosamides, and streptogramin type B antibiotics in Streptococcus sanguis

29 September 2017

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The ermC leader peptide: amino acid alterations leading to differential efficiency of induction by macrolide-lincosamide-streptogramin B antibiotics

29 September 2017

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alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

29 September 2017

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Fitting atomic models into electron-microscopy maps

2 June 2018

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Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

2 June 2018

1 reference

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Molecular mechanism of drug-dependent ribosome stalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4501

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4501

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4501

SIGNATURE: a single-particle selection system for molecular electron microscopy.

21 January 2018

1 reference

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Efficient protein selection based on ribosome display system with purified components.

21 January 2018

1 reference

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Multiparticle Cryo-EM of Ribosomes

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24662426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS4501

1 reference

Dimensions Publication ID

ADS bibcode

2014NatCo...5.3501A

0 references

1042325415

0 references

Fatcat ID

release_e6aaqiqa2rfa7jcg6zlzwcfv5e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e6aaqiqa2rfa7jcg6zlzwcfv5e

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

24662426

1 reference