Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment (Q27681270)

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

10 September 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

24 September 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

19 December 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

20 December 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

20 December 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

20 December 2018

1 reference

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative

20 December 2018

1 reference

20 December 2018

Burkholderia cenocepacia

object named as

Burkholderia cenocepacia

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Paul K Fyfe

0 references

Justyna Kalinowska-Tłuścik

object named as

Justyna Kalinowska-Tłuścik

0 references

Patrick E F O'Rourke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

10 January 2014

0 references

published in

BMC Structural Biology

1 reference

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31 May 2020

volume

1 reference

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31 May 2020

0 references

1 reference

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Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum

31 May 2020

cites work

1 reference

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Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

A Structure-Based Approach to Ligand Discovery for 2 C -Methyl- d -erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy †

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Biosynthesis of isoprenoids in plants: Structure of the 2C-methyl-d-erithrytol 2,4-cyclodiphosphate synthase fromArabidopsis thaliana. Comparison with the bacterial enzymes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

THE 1-DEOXY-D-XYLULOSE-5-PHOSPHATE PATHWAY OF ISOPRENOID BIOSYNTHESIS IN PLANTS

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development

20 March 2017

1 reference

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Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

20 March 2017

1 reference

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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

20 March 2017

1 reference

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REFMAC5 for the refinement of macromolecular crystal structures

20 March 2017

1 reference

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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Dali server: conservation mapping in 3D

20 March 2017

1 reference

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Features and development of Coot

20 March 2017

1 reference

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20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

1 reference

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Inference of macromolecular assemblies from crystalline state

20 March 2017

1 reference

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Scaling and assessment of data quality

20 March 2017

1 reference

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Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

20 March 2017

1 reference

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Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis

20 March 2017

1 reference

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Thiazolopyrimidine inhibitors of 2-methylerythritol 2,4-cyclodiphosphate synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927217

Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites

20 March 2017

1 reference

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ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

20 March 2017

1 reference

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The algal past and parasite present of the apicoplast

7 April 2017

1 reference

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Methylerythritol phosphate pathway of isoprenoid biosynthesis

29 September 2017

1 reference

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Target assessment for antiparasitic drug discovery

29 September 2017

1 reference

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The non-mevalonate pathway of isoprenoid precursor biosynthesis.

29 September 2017

1 reference

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Isoprenoid biosynthetic pathways as anti-infective drug targets

29 September 2017

1 reference

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Characterization of the depletion of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase in Escherichia coli and Bacillus subtilis

29 September 2017

1 reference

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The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates

29 September 2017

1 reference

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Identification of novel essential Escherichia coli genes conserved among pathogenic bacteria.

29 September 2017

1 reference

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Studies on new phosphonic acid antibiotics. I. FR-900098, isolation and characterization

29 September 2017

1 reference

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A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate.

29 September 2017

1 reference

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Biosynthesis of isoprenoids: a bifunctional IspDF enzyme from Campylobacter jejuni

2 June 2018

1 reference

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Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

2 June 2018

1 reference

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Identification of lethal mutations in Escherichia coli genes encoding enzymes of the methylerythritol phosphate pathway

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1472-6807-14-1

Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1472-6807-14-1

Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.

21 January 2018

1 reference

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The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.

27 November 2018

1 reference

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Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Shewanella oneidensis at 1.6 A: identification of farnesyl pyrophosphate trapped in a hydrophobic cavity

27 November 2018

1 reference

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Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24410837

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1472-6807-14-1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

1016974881

0 references

Fatcat ID

release_y6z6dcox6bb33oa7lakate67pa

1 reference

Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

24410837

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24410837%20AND%20SRC:MED&resulttype=core&format=json