Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases (Q27684637)

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English	Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases	scientific article

Statements

instance of

scholarly article

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title

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases (English)

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main subject

hypoxia

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author

Akane Kawamura

series ordinal

13

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Rasheduzzaman Chowdhury

series ordinal

1

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Christopher J. Schofield

series ordinal

18

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Nathan R Rose

object named as

Nathan R Rose

series ordinal

9

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Michael A McDonough

object named as

Michael A McDonough

series ordinal

7

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Peter J. Ratcliffe

object named as

Peter J Ratcliffe

series ordinal

17

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Ya-Min Tian

series ordinal

6

object named as

Ya-Min Tian

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Christopher J A Pugh

series ordinal

16

object named as

Christopher W Pugh

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Ana Conejo-García

series ordinal

10

object named as

Ana Conejo-Garcia

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Kar Kheng Yeoh

series ordinal

5

object named as

Kar Kheng Yeoh

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Anthony Tumber

series ordinal

8

object named as

Anthony Tumber

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Mun Chiang Chan

series ordinal

3

object named as

Mun Chiang Chan

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Marina Demetriades

series ordinal

11

object named as

Marina Demetriades

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author name string

José Ignacio Candela-Lena

series ordinal

2

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David Jeremy Greenald

series ordinal

4

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Sinnakaruppan Mathavan

series ordinal

12

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Myung Kyu Lee

series ordinal

14

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Freek van Eeden

series ordinal

15

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publication date

19 July 2013

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published in

ACS Chemical Biology

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volume

8

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issue

7

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page(s)

1488-96

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cites work

Phasercrystallographic software

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20 May 2022

reference URL

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

PROCHECK: a program to check the stereochemical quality of protein structures

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Selective inhibition of factor inhibiting hypoxia-inducible factor

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

High-resolution in situ hybridization to whole-mount zebrafish embryos

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Inhibition of 2-oxoglutarate dependent oxygenases

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Oxygen sensing by HIF hydroxylases

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Dipeptidyl-quinolone derivatives inhibit hypoxia inducible factor-1α prolyl hydroxylases-1, -2, and -3 with altered selectivity.

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

JmjC-domain-containing proteins and histone demethylation

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Coot: model-building tools for molecular graphics

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Expanding chemical biology of 2-oxoglutarate oxygenases

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Discovery of novel hydroxy-thiazoles as HIF-alpha prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation

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COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

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COCI

retrieved

12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Development of homogeneous luminescence assays for histone demethylase catalysis and binding.

1 reference

stated in

COCI

retrieved

12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Regulation of histone methylation by demethylimination and demethylation

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COCI

retrieved

12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

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COCI

retrieved

12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Processing of X-ray diffraction data collected in oscillation mode

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stated in

COCI

retrieved

12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

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COCI

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12 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

The human oxygen sensing machinery and its manipulation

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stated in

COCI

retrieved

12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Different modes of inhibitor binding to prolyl hydroxylase by combined use of X-ray crystallography and NMR spectroscopy of paramagnetic complexes

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stated in

COCI

retrieved

12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases

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stated in

COCI

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12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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stated in

COCI

retrieved

12 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1021/CB400088Q

Identifiers

DOI

10.1021/CB400088Q

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2621250

OpenCitations bibliographic resource ID

2621250

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2621250

PubMed publication ID

23683440

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2621250

ResearchGate publication ID

236917872

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