Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase (Q27673792)

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English	Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase	scientific article

Statements

instance of

scholarly article

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title

Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase (English)

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main subject

biophysics

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structural biology

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condensed matter physics

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author

Guennadi Kozlov

series ordinal

2

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Kalle Gehring

series ordinal

4

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author name string

Edna Matta-Camacho

series ordinal

1

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Marie Menade

series ordinal

3

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publication date

1 October 2012

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language of work

Acta Crystallographica Section F: Structural Biology Communications

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volume

68

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issue

Pt 10

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page(s)

1158-63

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cites work

Structure and function of a HECT domain ubiquitin-binding site

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PubMed Central

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Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

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20 March 2017

Structural basis of substrate recognition and specificity in the N-end rule pathway

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Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases

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20 March 2017

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

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20 March 2017

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

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Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD

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A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons

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Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

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EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response

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X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein

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Structure and function of the C-terminal PABC domain of human poly(A)-binding protein

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Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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20 March 2017

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

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20 March 2017

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

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REFMAC5 for the refinement of macromolecular crystal structures

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20 March 2017

Coot: model-building tools for molecular graphics

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20 March 2017

Pushing the boundaries of molecular replacement with maximum likelihood

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20 March 2017

The ubiquitin system

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20 March 2017

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

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20 March 2017

EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

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20 March 2017

Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs

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20 March 2017

Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response

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PubMed Central

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20 March 2017

BRCT domain-containing protein TopBP1 functions in DNA replication and damage response

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20 March 2017

EDD mediates DNA damage-induced activation of CHK2

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20 March 2017

Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain

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20 March 2017

Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.

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29 September 2017

Modulation of myocardin function by the ubiquitin E3 ligase UBR5.

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29 September 2017

The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates

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29 September 2017

Polyubiquitination by HECT E3s and the determinants of chain type specificity

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PubMed Central

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29 September 2017

The aggravating role of the ubiquitin-proteasome system in neurodegeneration

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29 September 2017

Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

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29 September 2017

The ubiquitin pathway for the degradation of intracellular proteins

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29 September 2017

Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis

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PubMed Central

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2 June 2018

Ubiquitin and its role in neurodegeneration.

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2 June 2018

The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin

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21 January 2018

In vitro assembly and recognition of Lys-63 polyubiquitin chains

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21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

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21 January 2018

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

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21 January 2018

Letter to the editor: 1H, 15N and 13C resonance assignments for the catalytic domain of the yeast E2, UBC1

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the ubiquitin interfacial residues in a ubiquitin-E2 covalent complex

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reference URL

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inferred from PubMed ID database lookup

Identifiers

DOI

10.1107/S1744309112036937

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

826403

OpenCitations bibliographic resource ID

826403

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

826403

PMC publication ID

3497971

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

826403

PubMed publication ID

23027739

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

826403

 

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