X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinase (Q27672770)

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John S Sack

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Nazia Ahmed

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James Burke

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Chiehying Y Chang

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Mian Gao

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Joseph Tino

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Dianlin Xie

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Andrew J Tebben

Chemical Biology and Drug Design

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publication date

November 2011

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published in

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volume

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issue

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page(s)

739-48

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cites work

Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Itk and Th2 responses: action but no reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Selective Itk inhibitors block T-cell activation and murine lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Targeting IL-6 in the treatment of inflammatory and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Human single-domain neutralizing intrabodies directed against Etk kinase: a novel approach to impair cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Pushing the boundaries of molecular replacement with maximum likelihood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Rational design of inhibitors that bind to inactive kinase conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Comparative Analysis of Mutant Tyrosine Kinase Chemical Rescue † ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X

Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01230.X