Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases (Q27679885)

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English	Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases	scientific article

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Europe PubMed Central

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3863620

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20 February 2020

title

Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases (English)

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Europe PubMed Central

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3863620

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20 February 2020

main subject

structural biology

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author

Randall Mcnally

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3

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Europe PubMed Central

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3863620

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20 February 2020

Julia M Rogers

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5

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3863620

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20 February 2020

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Angela V Toms

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1

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3863620

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20 February 2020

Anagha Deshpande

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2

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3863620

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20 February 2020

Youngjee Jeong

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4

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3863620

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20 February 2020

Chae Un Kim

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6

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3863620

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20 February 2020

Sol M Gruner

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7

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3863620

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20 February 2020

Scott B Ficarro

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8

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20 February 2020

Jarrod A Marto

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9

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3863620

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20 February 2020

Martin Sattler

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10

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3863620

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20 February 2020

James D Griffin

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11

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3863620

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20 February 2020

Michael J Eck

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12

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3863620

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20 February 2020

publication date

8 September 2013

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3863620

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20 February 2020

published in

Nature Structural & Molecular Biology

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3863620

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20 February 2020

volume

20

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3863620

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20 February 2020

issue

10

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3863620

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20 February 2020

page(s)

1221-1223

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20 February 2020

cites work

Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

Janus kinases in immune cell signaling

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

The protein kinase complement of the human genome

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

20 March 2017

A gain-of-function mutation of JAK2 in myeloproliferative disorders

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

7 April 2017

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

7 April 2017

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

7 April 2017

Modular evolution of phosphorylation-based signalling systems

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

The JAK2 exon 12 mutations: A comprehensive review

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

The constitutive activation of Jak2-V617F is mediated by a π stacking mechanism involving phenylalanines 595 and 617.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

A JAK2 interdomain linker relays Epo receptor engagement signals to kinase activation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

JAK mutations in high-risk childhood acute lymphoblastic leukemia

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Kinome signaling through regulated protein-protein interactions in normal and cancer cells

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Hematopoietic cytokine receptor signaling

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Jak2: normal function and role in hematopoietic disorders

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

29 September 2017

Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

27 November 2018

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

27 November 2018

Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

27 November 2018

Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

27 November 2018

A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3863620

retrieved

27 November 2018

Identifiers

DOI

10.1038/NSMB.2673

2 references

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1269523

stated in

Europe PubMed Central

PMC publication ID

3863620

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24013208%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 February 2020

Dimensions Publication ID

1042609396

0 references

OpenCitations bibliographic resource ID

1269523

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1269523

PMC publication ID

3863620

2 references

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1269523

stated in

Europe PubMed Central

PMC publication ID

3863620

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24013208%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 February 2020

PubMed publication ID

24013208

2 references

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1269523

stated in

Europe PubMed Central

PMC publication ID

3863620

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24013208%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 February 2020

ResearchGate publication ID

256468993

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