Structural Basis for Regulation of Human Glucokinase by Glucokinase Regulatory Protein (Q27679719)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Structural basis for regulation of human glucokinase by glucokinase regulatory protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Brian G Miller

1 reference

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7 March 2020

language of work or name

English

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publication date

26 August 2013

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7 March 2020

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7 March 2020

volume

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7 March 2020

issue

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7 March 2020

page(s)

6232-6239

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Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase

7 March 2020

cites work

1 reference

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Crystal structure of glucokinase regulatory protein

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Homotropic allosteric regulation in monomeric mammalian glucokinase

20 March 2017

1 reference

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20 March 2017

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20 March 2017

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Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

20 March 2017

1 reference

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Inference of macromolecular assemblies from crystalline state

20 March 2017

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The atomic structure of protein-protein recognition sites

20 March 2017

1 reference

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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

20 March 2017

1 reference

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Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Characterization of glucokinase regulatory protein-deficient mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

20 March 2017

1 reference

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

20 March 2017

1 reference

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Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Order-disorder transitions govern kinetic cooperativity and allostery of monomeric human glucokinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Assessing the potential of glucokinase activators in diabetes therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Extremes of clinical and enzymatic phenotypes in children with hyperinsulinism caused by glucokinase activating mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Biophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: impact of physiological and pharmacological effectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Glucokinase and molecular aspects of liver glycogen metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Diabetes mellitus and genetically programmed defects in beta-cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Demonstration of a slow conformational change in liver glucokinase by fluorescence spectroscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

The regulatory protein of liver glucokinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Low-resolution refinement tools in REFMAC5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Activating mutations in the human glucokinase gene revealed by genetic selection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

The regulatory protein of glucokinase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Effectors of the regulatory protein acting on liver glucokinase: a kinetic investigation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Familial hyperinsulinism caused by an activating glucokinase mutation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

23-Residue C-terminal alpha-helix governs kinetic cooperativity in monomeric human glucokinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Allosteric activators of glucokinase: potential role in diabetes therapy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859847

Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23957911

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI400838T

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

23957911

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957911%20AND%20SRC:MED&resulttype=core&format=json