Structure of the DNA Repair Helicase XPD (Q27650710)

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Kenneth A Johnson

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Stephen A McMahon

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Muse Oke

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Lester Carter

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Anne-Marie McRobbie

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Sara E Brown

The X-ray crystal structure of RNA polymerase from Archaea

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language of work or name

English

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publication date

30 May 2008

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published in

Cell

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volume

133

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issue

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page(s)

801-12

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cites work

1 reference

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Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair

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Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products

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The DNA repair helicases XPD and FancJ have essential iron-sulfur domains

20 March 2017

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Nucleotide excision repair/TFIIH helicases RAD3 and SSL2 inhibit short-sequence recombination and Ty1 retrotransposition by similar mechanisms

20 March 2017

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Complete Genome Sequence of an Aerobic Thermoacidophilic Crenarchaeon, Sulfolobus tokodaii strain7

20 March 2017

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The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases

20 March 2017

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Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

20 March 2017

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Structure and mechanism of helicases and nucleic acid translocases

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Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase

7 April 2017

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An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria

29 September 2017

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Archaeal DNA replication and repair

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Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4)photoproducts

29 September 2017

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DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

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Xpd, a Structural Bridge and a Functional Link

29 September 2017

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Modularity and specialization in superfamily 1 and 2 helicases

29 September 2017

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Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene

29 September 2017

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A temperature-sensitive disorder in basal transcription and DNA repair in humans

29 September 2017

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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

29 September 2017

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The cancer-free phenotype in trichothiodystrophy is unrelated to its repair defect

29 September 2017

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TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.

29 September 2017

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Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription

29 September 2017

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Analysis of mutations in the XPD gene in Italian patients with trichothiodystrophy: site of mutation correlates with repair deficiency, but gene dosage appears to determine clinical severity

29 September 2017

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Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene.

29 September 2017

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Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III

29 September 2017

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Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome

29 September 2017

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Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients

2 June 2018

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An iron-sulfur cluster in the family 4 uracil-DNA glycosylases

2 June 2018

1 reference

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The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction

2 June 2018

1 reference

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An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis

27 November 2018

1 reference

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The DinG protein from Escherichia coli is a structure-specific helicase.

27 November 2018

1 reference

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DNA-bound redox activity of DNA repair glycosylases containing [4Fe-4S] clusters

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326533

Xpd/Ercc2 regulates CAK activity and mitotic progression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326533

Production of selenomethionine-labelled proteins using simplified culture conditions and generally applicable host/vector systems

27 November 2018

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12 December 2020

Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy

1 reference

12 December 2020

Xeroderma pigmentosum and Cockayne syndrome

1 reference

12 December 2020

Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features

1 reference

12 December 2020

10.1016/J.CELL.2008.04.029

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

18510925

1 reference