Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution (Q27645585)

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Yan Xu

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Yuuki Noguchi

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Hiroshi Sugiyama

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Masato Katahira

Telomere states and cell fates

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language of work or name

English

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publication date

July 2007

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published in

FEBS Journal

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volume

274

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issue

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page(s)

3545-56

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cites work

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TRF2 Protects Human Telomeres from End-to-End Fusions

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Telomere dysfunction increases mutation rate and genomic instability

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

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The terminal DNA structure of mammalian chromosomes

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Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

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Extension of G-quadruplex DNA by ciliate telomerase

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G-Quadruplex DNA as a target for drug design

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Telomere maintenance as a target for anticancer drug discovery

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DNA and its associated processes as targets for cancer therapy

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G-quadruplex interacting agents targeting the telomeric G-overhang are more than simple telomerase inhibitors

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Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

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Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure

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Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

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Crystal structure of parallel quadruplexes from human telomeric DNA

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An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction

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Intramolecular Higher Order Packing of Parallel Quadruplexes Comprising a G:G:G:G Tetrad and a G(:A):G(:A):G(:A):G Heptad of GGA Triplet Repeat DNA

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Method for direct discrimination of intra- and intermolecular hydrogen bonds, and characterization of the G(:A):G(:A):G(:A):G heptad, with scalar couplings across hydrogen bonds

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Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

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Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold

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Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

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(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex

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Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR

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Structural basis of the highly efficient trapping of the HIV Tat protein by an RNA aptamer

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Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex

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Characterization of structure and stability of long telomeric DNA G-quadruplexes

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