Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs (Q27639212)

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Enzymes work by solvation substitution rather than by desolvation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Energetics of enzyme catalysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Prediction of functionally important residues based solely on the computed energetics of protein structure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Analysis of the steric strain in the polypeptide backbone of protein molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Effect of active site residues in barnase on activity and stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

A relationship between protein stability and protein function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Stability and function: two constraints in the evolution of barstar and other proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Remarkable activity enhancement of thermolysin mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Stability of TEM beta-lactamase mutants hydrolyzing third generation cephalosporins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

A natural polymorphism in β-lactamase is a global suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfolding and aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Noncovalent interaction energies in covalent complexes: TEM-1 ?-lactamase and ?-lactams

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Predicting the emergence of antibiotic resistance by directed evolution and structural analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEM(pUC19) beta-lactamase from Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Structural basis for the inactivation of the P54 mutant of beta-lactamase from Staphylococcus aureus PC1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Directed evolution of a thermostable esterase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Selection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Extreme functional sensitivity to conservative amino acid changes on enzyme exteriors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Amino acid sequence determinants of beta-lactamase structure and activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Rapid evolution of a protein in vitro by DNA shuffling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

7 January 2021

Protein stability curves

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Processing of X-ray diffraction data collected in oscillation mode

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

AMoRe: an automated package for molecular replacement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900400-X

10.1016/S0022-2836(02)00400-X

7 January 2021

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fwcxcwnh25exlgoyngbascyt3q

mapped directly with Wikidata item

30 July 2022

based on heuristic

Fatcat ID

release_fwcxcwnh25exlgoyngbascyt3q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fwcxcwnh25exlgoyngbascyt3q

mapped directly with Wikidata item

30 July 2022

based on heuristic

OpenCitations bibliographic resource ID

584003

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

584003

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/fwcxcwnh25exlgoyngbascyt3q