The TGF beta receptor activation process: an inhibitor- to substrate-binding switch (Q27635175)

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T W Muir

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L Xu

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Y G Chen

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J Kuriyan

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J Massagué

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

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publication date

September 2001

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671-82

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

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TGF-beta signal transduction

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