Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity (Q27626519)

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English	Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity	scientific article

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instance of

scholarly article

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title

Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity (English)

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author name string

W Shakespeare

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1

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M Yang

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2

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R Bohacek

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3

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F Cerasoli

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4

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K Stebbins

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5

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R Sundaramoorthi

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6

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M Azimioara

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7

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C Vu

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8

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S Pradeepan

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9

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C Metcalf

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10

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C Haraldson

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11

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T Merry

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12

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D Dalgarno

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13

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S Narula

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14

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M Hatada

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15

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X Lu

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16

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M R van Schravendijk

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17

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S Adams

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18

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S Violette

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19

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J Smith

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20

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W Guan

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21

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C Bartlett

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22

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J Herson

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23

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J Iuliucci

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24

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M Weigele

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25

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T Sawyer

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26

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language of work or name

English

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publication date

15 August 2000

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published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

97

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issue

17

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page(s)

9373-8

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cites work

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

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Src family kinases are required for integrin but not PDGFR signal transduction.

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An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

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A Src SH2 selective binding compound inhibits osteoclast-mediated resorption.

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An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing SRC SH2 ligand.

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Src homology-2 domains: structure, mechanisms, and drug discovery

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based on heuristic

inferred from PubMed ID database lookup

The formation of a covalent complex between a dipeptide ligand and the src SH2 domain

1 reference

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PubMed

reference URL

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retrieved

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.97.17.9373

1 reference

stated in

Fatcat

reference URL

https://api.fatcat.wiki/v0/release/v3hb4jf2kfftdgtge2unicsjwu

retrieved

30 July 2022

based on heuristic

mapped directly with Wikidata item

ADS bibcode

2000PNAS...97.9373S

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Fatcat ID

release_v3hb4jf2kfftdgtge2unicsjwu

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stated in

Fatcat

reference URL

https://api.fatcat.wiki/v0/release/v3hb4jf2kfftdgtge2unicsjwu

retrieved

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

16871

1 reference

stated in

Fatcat

reference URL

https://api.fatcat.wiki/v0/release/v3hb4jf2kfftdgtge2unicsjwu

retrieved

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

10944210

1 reference

stated in

Fatcat

reference URL

https://api.fatcat.wiki/v0/release/v3hb4jf2kfftdgtge2unicsjwu

retrieved

30 July 2022

based on heuristic

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ResearchGate publication ID

12376997

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