Guanine nucleotide exchange factor GET3 YDL100C (Q27552640)

hierarchical database ID heuristic

2 October 2019

based on heuristic

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

unfolded protein binding

1 reference

9 May 2019

The protein targeting factor Get3 functions as ATP-independent chaperone under oxidative stress conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

guanyl-nucleotide exchange factor activity

1 reference

9 May 2019

Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

protein binding

15 references

9 May 2019

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

An in vivo map of the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

A comprehensive two-hybrid analysis to explore the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Crystal Structure of Get4-Get5 Complex and Its Interactions with Sgt2, Get3, and Ydj1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

The structural basis of tail-anchored membrane protein recognition by Get3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

The GET complex mediates insertion of tail-anchored proteins into the ER membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

The mechanism of membrane-associated steps in tail-anchored protein insertion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

identical protein binding

6 references

9 May 2019

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

The structural basis of tail-anchored membrane protein recognition by Get3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Model for eukaryotic tail-anchored protein binding based on the structure of Get3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

3 references

9 May 2019

9 May 2019

The Saccharomyces cerevisiae Arr4p is involved in metal and heat tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

cell component

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12154&geneProductId=UniProtKB:Q12154

1 reference

7 November 2018

GET complex

1 reference

27 March 2018

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

SGD

S000002258

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12154&geneProductId=UniProtKB:Q12154

GET complex

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

cytosol

HDA

1 reference

9 May 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

posttranslational protein targeting to endoplasmic reticulum membrane

HDA

biological process

1 reference

16 July 2018

A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

SGD

S000002258

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12154&geneProductId=UniProtKB:Q12154

response to arsenic-containing substance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

response to metal ion

1 reference

9 May 2019

The Saccharomyces cerevisiae Arr4p is involved in metal and heat tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

9 May 2019

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

IGI

9 May 2019

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

1 reference

9 May 2019

pheromone-dependent signal transduction involved in conjugation with cellular fusion

1 reference

9 May 2019

Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

response to heat

1 reference

9 May 2019

The Saccharomyces cerevisiae Arr4p is involved in metal and heat tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

protein insertion into ER membrane

1 reference

27 March 2018

The GET complex mediates insertion of tail-anchored proteins into the ER membrane

SGD

S000002258

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12154&geneProductId=UniProtKB:Q12154

posttranslational protein targeting to endoplasmic reticulum membrane

tail-anchored membrane protein insertion into ER membrane

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12154

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

3.A.21.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database