Alpha-1,2-mannosidase MNL1 YHR204W (Q27549758)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38888

Seven-hairpin glycosidases

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38888

Six-hairpin glycosidase-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38888

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

14 February 2019

14 February 2019

A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

14 February 2019

A complex of Pdi1p and the mannosidase Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

alpha-mannosidase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

hydrolase activity, acting on glycosyl bonds

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38888&geneProductId=UniProtKB:P38888

1 reference

10 September 2018

endoplasmic reticulum quality control compartment

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

Golgi membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38888&geneProductId=UniProtKB:P38888

1 reference

27 February 2018

mannose trimming involved in glycoprotein ERAD pathway

IBA

biological process

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

14 February 2019

A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

14 February 2019

A complex of Pdi1p and the mannosidase Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

IGI

14 February 2019

A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

response to unfolded protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

protein alpha-1,2-demannosylation

1 reference

14 February 2019

A complex of Pdi1p and the mannosidase Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

protein glycosylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

endoplasmic reticulum mannose trimming

1 reference

14 February 2019

A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38888

1 reference

14 February 2019

N-glycan processing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38888&geneProductId=UniProtKB:P38888

1 reference

27 February 2018

ubiquitin-dependent glycoprotein ERAD pathway

IBA

2 references

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference